Spinosyn D, >90% (6-methyl-spinosyn A) is the minor component of Spinosad and makes up to 15% of Spinosad. Spinosyn D differs from Spinosyn A by having a methyl group instead of a hydrogen atom at position C6 on the macrolide. Spinosyn D is a potent insecticide for crop protection. The spinosyns have a unique mode of action involving disruption of nicotinic acetylcholine receptors.
Spinosyn D is soluble in ethanol, methanol, DMF and DMSO.
For other Spinosyn products, click here.
|Mechanism of Action||Spinosyn A resembles a GABA antagonist and is comparable to the effect of avermectin on insect neurons.|
|Plant Biology Applications||
Spinosad is a natural product approved for use in organic agriculture as an insecticide and crop protectant. It has an excellent environmental and mammalian toxicological profile.
Kirst HA (2010) The spinosyn family of insecticides: Realizing the potential of natural products research. J. Antibiotics 63:101-111
Kirst HA et al (191) A 83543A-D, unique fermentation-derived tetracyclic macrolides. Tetrahedron Lett. 32:4839
Lopez O and Fernandez-Bolanos JG ed. (2011) The Spinosyn insecticides. In: Green trends in insect control. RSC Green Chemistry Series No. 11, RSC Publishing, Ch. 5: pp 163-212