Temocillin Disodium is the salt of Temocillin, a semisynthetic, β-lactamase-resistant carboxypenicillin antimicrobial. Temocillin is the 6-alpha-methoxy derivative of ticarcillin. Temocillin is is used as an alternative to carbapenems and is primarily effective against Gram-negative bacteria. Temocillin Disodium is soluble in water.