Epichlortetracycline is a degradation product of chlorotetracycline formed by acid-catalysed isomerisation of the dimethylamino group at C4. Epichlortetracycline exhibits little antibiotic activity but its abundance is indicative of poor storage and handling of chlortetracycline.
Epichlortetracycline is soluble in ethanol, methanol, DMF or DMSO. Good water solubility.
Epichlortetracycline is soluble in ethanol, methanol, DMF or DMSO. Good water solubility.
| Molecular Formula | C22H24Cl2N2O8 |
| References | Quantitative analysis of chlortetracycline and related substances by high-performance liquid chromatography. Kahn N.H. et al. J. Pharm. Biomed. Anal. 1989, 7, 339. Separation of keto-enol tautomers of chlortetracycline and 4-epichlortetracycline by liquid chromatography on poly(styrene-divinylbenzene)copolymer. Naidong W. J. Pharm Biomed Anal. 1990, 8, 881. |
