7-Dechlorogriseofulvin is co-produced with griseofulvin by Penicillium sp.. 7-Dechlorogrisefulvin has antifungal activity, albeit less potent than griseofulvin. 7-Dechlorogriseofulvin inhibits HCT116, MCF-7 and K562 cell lines, inducing apoptosis.
| Molecular Formula | C17H18O6 |
| References |
Choo Y-H et al (2010) Identification of the viridicatumtoxin and griseofulvin gene clusters from Penicillium aethiopicum. Chem. Biol. 17:483 Hazalin NA et al (2012) Induction of apoptosis against cancer cell lines by four ascomycetes (endophytes) from Malaysian rainforest. Phytomed. 19:609 Zhao JH et al (2012) Bioactive secondary metabolites from Nigrospora sp. LLGLM003, an endophytic fungus of the medicinal plant Moringa oleifera Lam. World J. Microbiol. Biotechnol. 28:2107 |
