Caffeic acid phenethyl ester is a natural phenolic compound from honeybee hives and has demonstrated anti-carcinogenic, anti-bacterial, and antiinflammatory properties.
| Mechanism of Action | Caffeic acid phenethyl ester inhibits bacterial growth by the production of reactive oxygen species (ROS) which disrupt the cell's outer membrane. Anti-inflammatory effects of CAPE arise from inhibiting the release of arachidonic acid from the cell membrane as well as inhibition of COX-1 and COX-2 activity. |
| Spectrum | Caffeic acid phenethyl ester is active against Enterococcus faecalis, Listeria monocytogenes, Staphylococcus aureus, and Haemophilus influenzae. |
| References | Murtaza, Ghulam, Sabiha Karim, Muhammad Rouf Akram, Shujaat Ali Khan, Saira Azhar, Amara Mumtaz, and Muhammad Hassham Hassan Bin Asad. "Caffeic Acid Phenethyl Ester and Therapeutic Potentials." BioMed Research International 2014 (2014): 1-9. Web. |
