The tetronic acid, chlorothricin, is an unusual macrocyclic antibiotic from a Streptomyces sp., related to kijanimicin, saccharocarcins, tetrocarcins and versipelostatin. Chlorothricin inhibits cholesterol biosynthesis from mevalonate and inhibits pyruvate carboxylases purified from rat liver, chicken liver and Azotobacter vinelandii.
Chlorothricin is soluble in ethanol, methanol, DMF and DMSO.
Chlorothricin is soluble in ethanol, methanol, DMF and DMSO.
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