SKU: S125  / 
    CAS Number: 2098376-42-0

    Stachybotrysin B

    $207.00 - $725.00

    Stachybotrysin B is an analogue of a complex of phenylspirodrimanes isolated from the fungus, Stachybotrys chartarum, by collaborating Chinese Key Research Institutes in 2017. Stachybotrysin B is active against HIV but is not cytotoxic.
    Stachybotrysins have been shown to inhibit osteoclast differentiation in bone marrow macrophage cells via suppression of
    RANKL-induced activation of p-ERK, p-JNK, p-p38, c-Fos, and NFATc1.

    Molecular Formula  C25H34O6

    Zhao J et al (2017)  Stachybotrysins A-G, phenylspirodrimane derivatives from the fungus Stachybotrys chartarum. J.Nat. Prod. 80:1819.

    Kim JW et al (2016)  Stachybotrysin, an osteoclast differentiation inhibitor from the marine-derived fungus Stachybotrys sp. KCB13F013. J. Nat. Prod. 79:2703