SKU: E065  / 
    CAS Number: 989-51-5

    Epigallocatechin Gallate

    RM387.37 - RM707.37

    Epigallocatechin Gallate, the catechin found in green tea (Camellia sinensis), has been reported to have an exhaustive list of promising bioactivity. It has antiparasitic activity against Leishmania, antiviral activity against influenza A and hepatitis B viruses, and antifungal activity against Candida albicans. Epigallocatechin Gallate has has anti-inflammatory effects and can induce apoptosis selectively to transformed cells for potential anticancer activity.

    Epigallocatechin Gallate is soluble in water.

    Spectrum Broad-spectrum activity against Gram-negative and Gram-positive bacteria including methicillin-resistant Staphylococcus aureus.
    References Gordon NC and Wareham DW (2010)  Antimicrobial activity of the green tea polyphenol (−)-epigallocatechin-3-gallate (EGCG) against clinical isolates of Stenotrophomonas maltophilia. Int. J. Antimicrob. Agents 36(2):129-131

    Hirasawa M and Takada K (2004). Multiple effects of green tea catechin on the antifungal activity of antimycotics against Candida albicans. J. Antimicrob. Chemother. 53(2):225-229

    Inacio JD, Gervazoni L, Canto-Cavalheiro MM and Almeida-Amaral EE (2014). The Effect of (-)-Epigallocatechin 3-O - Gallate in vitro and in vivo in Leishmania braziliensis: Involvement of reactive oxygen species as a mechanism of action. PLoS Negl. Trop. Dis. 8(8)

    Steinmann J, Buer J, Pietschmann T and Steinmann E (2013). Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea. Br. J. Pharmacol. 168(5):1059-1073

    Wang YC and Bachrach U (2002) The specific anti-cancer activity of green tea (−)-epigallocatechin-3-gallate (EGCG). Amino Acids 22(2):131-143

    Zhong Y, Chiou Y, Pan M and Shahidi F (2012)  Anti-inflammatory activity of lipophilic epigallocatechin gallate (EGCG) derivatives in LPS-stimulated murine macrophages. Food Chem. 134(2):742-748