SKU: E017  / 
    CAS Number: 183319-69-9

    Erlotinib hydrochloride

    $99.42 - $333.35

    Erlotinib hydrochloride is a drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer. It is a tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).

    Mechanism of ActionErlotinib is an epidermal growth factor receptor (EGFR) inhibitor. Erlotinib specifically targets the EGFR tyrosine kinase ATP binding site, which is highly expressed and occasionally mutated in various forms of cancer. Erlotinib prevents EGFR homodimer formation, a conformational change required for signal transmittance.
    Molecular FormulaC22H23N3O4
    SolubilityWater: Very slightly soluble
    Acid (pH 2): 0.4 mg/mL
    Note: Maximum solubility can be attained by plain water at 0.8 mg/mL