Ivermectin B1a Monosaccharide is a semi-synthetic compound produced by selective hydrolysis of the terminal saccharide unit of ivermectin. Ivermectin monosaccharide is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. The monosaccharide is used as a sensitive probe for the detection of some types of ivermectin resistance.
Ivermectin B1a Monosaccharide is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
| References | Ivermectin, a new broad-spectrum antiparasitic agent. Chabala J.C. et al. J. Med. Chem. 1980, 23, 1134. Detection of resistance to ivermectin in Haemonchus contortus. Gill J.G. et al. Int. J. Parasit. 1991, 21, 771. |
