O-Methylviridicatin is a natural derivative of the alkaloid mycotoxin viridicatin produced by several species of Penicillium. The scaffold of quinolin-2(1H)-one is a useful structural motif found in many natural products. In particular, derivatives of 4-arylquinolinones have attracted attention for their anticancer/antiviral activities. O-Methylviridicatin is a fungal metabolite that can inhibit the tumor necrosis factor alpha (TNFα)-induced replication of HIV.
O-Methylviridicatin is soluble in ethanol, methanol, DMSO and DMF but is practically insoluble in water.