SKU: P158  / 
    CAS Number: 98985-76-3

    Piliformic Acid

    RM1,289.63 - RM4,506.56

    Piliformic Acid is produced by fungi including Xylaria sp. Piliformic acid has mild inhibitory activity against Propionobacterium acnes, inhibiting the P. acnes-induced pro-inflammatory cytokines production in THP-1 cells. Piliformic acid is active against the plant fungal pathogen Colletotrichum gloeosporioides with MIC 2.92 μmol/mL and has antileishmanial activity.

    Molecular Formula  C11H18O4
    References

    Anderson JR et al (1985)  Metabolites of the higher fungi. Part 22. 2-Butyl-3-methylsuccinic acid and 2-hexylidene-3-methylsuccinic acid from xylariaceous fungi. J Chem Soc Perkin Trans. 1:1481

    Barros CB et al  (2018)  Leishmanicidal compounds of Nectria pseudotrichia, an endophytic fungus isolated from the plant Caesalpinia echinata (Brazilwood). Mem. Inst. Oswaldo Cruz. 113:102

    Elias LM et al (2018)  The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose. Braz. J. Microbiol. 49:840