SKU: P095  / 
    CAS Number: 12650-69-0

    Pseudomonic Acid

    $186.00 - $650.50

    Pseudomonic Acid is a potent antibiotic produced by Pseudomonas fluorescens.  Pseudomonic Acid has broad-spectrum activity against Gram-positive bacteria.

    Pseudomonic Acid is soluble in ethanol, methanol, DMF and DMSO.  It has limited water solubility.

    Mechanism of Action Pseudomonic acid acts as a potent and selective inhibitor of isoleucyl-tRNA synthetase.

    Fuller AT et al (1971)  Pseudomonic acid: an antibiotic produced by Pseudomonas fluorescens. Fuller Nature 234:416

    Hughes J and Mellows G (1978)  Inhibition of isoleucyl-transfer ribonucleic acid synthetase in Echerichia coli by pseudomonic acid. Biochem. J. 176:305

    Sutherland R (1985)  Antibacterial activity of mupirocin (pseudomonic acid), a new antibiotic for topical use. Antimicrob. Agents Chemother. 27:495