SKU: P127-10G  / 
    CAS Number: 5685-86-9

    Pyrantel Citrate

    S/.996.30

    Pyrantel Citrate is a thiophene and anthelmintic agent. It has been used to characterize Ancylostoma caninum isolates. It was described in 1965 by researchers at Pfizer. Pyrantel and its analogs (oxantel and morantel) are members of the tetrahydropyrimidine family. Other salt forms include tartrate and pamoate salt, with the pamoate salt frequently used in veterinary research.  Pyrantel is a nicotinic agonist for the acetylcholine (ACh) receptor.  It is also a cholinesterase inhibitor.

    Pyrantel Citrate is freely soluble in water.

    We also offer:

    • Pyrantel Pamoate (P129)
    • Pyrantel (+) Tartrate (P082)
    Mechanism of Action

    Pyrantel Citrate activates the excitatory nicotinic acetylcholine (nACh) receptor causing spastic paralysis of suceptible nematodes.

    Spectrum Pyrantel Citrate has activity against parasites including pinworm, hookworm, roundworm and others.
    Molecular Formula C11H14N2S · C6H8O7
    References

    Kopp SR et al (2008) Pyrantel in small animal medicine: 30 years on. Vet. J. 178(2):177-184

    Sheehan DJ, Sheehan SM, and Marchiondo AA (2016) Discovery and chemistry of Pyrantel, morantel and oxantel. In: Pyrantel Parasiticide therapy in humans and domestic animals. Ch. 1 pp. 1-19

    Martin RJ and Geary TG (2016) Pharmacology of Pyrantel. In: Pyrantel parasiticide therapy in humans and domestic animals. Ch.2. pp. 21-45