Bioactive small molecules are organic compounds that have a low molecular weight (900 daltons). Most pharmaceutical drugs are small molecules. Larger structures such as nucleic acids, proteins, and many polysaccharides are not small molecules.
Siomycin is a macrocyclic thiopeptide antibiotic with potent and selective antibacterial activity first isolated from the fermentation product of Streptomyces sioyaensis by Nishimura in 1959. This member of the thiostrepton family is a potent inhibitor...
Ceftiofur Sodium is the sodium salt of Ceftiofur, a broad-spectrum, third-generation β-lactamase resistant cephalosporin first described in 1987, commonly used in veterinary research applications. Its metabolite (desfurolyceftiofur) also has...
Isoniazid is a bactericidal and bacteriostatic agent against Mycobacterium tuberculosis, the causal agent of tuberculosis. It is a pyridine in structure. Mechanism of Action Isoniazid itself is not toxic to the bacterial cell, but acts as...
Tetramisole Hydrochloride (syn: DL-Levamisole) is a racemic mixture composed of 50% D- and 50% L-isomers of Levamisole. This compound is less potent than Levamisole Hydrochloride against parasites., and the D-isomer of the mixture contributes its...
Mitoxantrone Dihydrochloride is used for cancer research as a chemotherapeutic for leukemias and solid tumors. It has immunosuppressive activity and inhibits proliferation of lymphocytes and induces apoptosis of antigen-presenting T-cells...
Rapamycin (Sirolimus) is a natural compound belonging to the macrolide family. It is derived from Streptomyces hygroscopicus isolated from a soil sample from Easter Island in 1972 by Mr. Sehgal of Ayerst Research Labs in Montreal, Quebec...
Sulfisoxazole is a bioactive small molecule and broad-spectrum sulfanilamide antibacterial agent with an oxazole substituent. It is an ETA selective endothelin receptor antagonist (ETAR antagonist). It is a synthetic analog of the natural compound...
Cinacalcet HCl is the hydrochloride salt of the Type II calcimimetic compound Cinacalcet. Cinacalcet is a modulator of parathyroid hormone secretion. Cinacalcet is able to increase the cytoplasmic concentration of Ca2+. Cinacalcet Hydrochloride is an...
Quetiapine Fumarate is an inhibitor of dopamine and serotonin. Serotonin is a neurotransmitter thought to play a role in depression and schizophrenia. Classified as a Dangerous Good. May be subject to additional shipping charges. Contact us for details...
Tolvaptan is a non-peptide aquaretic agent that functions as a selective, competitive vasopressin receptor 2 (v2) antagonist. Aquaretic agents are being studied for water-retaining disorders like congestive heart failure and live cirrhosis. Tolvaptan has...
Rocuronium Bromide is the bromide salt form of Rocuronium, a fumarate, aminosteroid type non-depolarizing neuromuscular blocking agent that relaxes the skeletal muscle. It was introduced in 1994, and has a similar pharmacokinetic profile to...
Oxiracetam is nootropic agent of the racetam family, a cyclic derivative of γ-aminobutyric acid (GABA) the chief inhibitory neurotransmitter in mammals. It has been shown to improve memory and learning in mouse models. In pharma, it is...
