Bioactive small molecules are organic compounds that have a low molecular weight (900 daltons). Most pharmaceutical drugs are small molecules. Larger structures such as nucleic acids, proteins, and many polysaccharides are not small molecules.
Fondaprinux is sulfated pentasaccharide, an ultra low molecular weight synthetic form of heparain with antithrombotic properties. It is analogous to the pentasaccharide sequence in heparin. Mechanism of Action Fondaprinux Sodium binds...
Mosapride Citrate, developed by Takeda, is a gastroprokinetic agent that enhances gastrointestinal motility, and exerts anti-inflammatory effects on the GI tract. It acts as a 5-HT4 receptor agonist and 5-HT3 receptor antagonist. Mechanism of...
Alvimopan is a gastroprokinetic peripherally restricted mu-opioid receptor antagonist (MOR). It has a favorable kinetic activity (0.2 ng/ml) and dissociates more slowly than most other ligands.Mechanism of ActionAlvimopan competitively binds to the...
Argatroban is a synthetic small molecule and potent thrombin inhibitor that functions as an anticoagulant agent. It can protect against thrombosis by limiting clot formation.Mechanism of ActionArgatroban is able to inhibit thrombin directly and...
