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Leptomycin B is the dominant member of the Leptomycin class, secondary metabolites isolated from selected Streptomyces strains. It is a bioactive small molecule with antifungal and antibacterial...
Menadione Sodium Bisulfite (syn: Vitamin K3) is the metabolic precursor to Vitamin K2 in mammals. It belongs to the class 1,4-naphthoquinones, specifically a 1,4-naphthoquinone, which is substituted...
Chaetocin is an epithiodioxopiperazine antibiotic that has recently shown promise as a selective antitumor agent. Chaetocin is dramatically accumulated in cancer cells via a process inhibited by...
Menadione (Vitamin K3) is the precursor to vitamin K2 in mammals. It has also been tested as a possible anticancer agent able to induce apoptosis. Menadione is suitable for microbiology use. We...
Kijanimicin is a tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin. Like the tetrocarcins, kijanimicin contains an unusual nitroaminoglycoside. Kijanimicin is a...
Albofungin is a polyaromatic heterocycle containing a rare N-aminoamide, isolated from a Streptomyces species in Russia in 1959. Albofungin exhibits a broad biological profile with antibiotic,...
Doxorubicin (syn: Adriamycin) is the most extensively studied of a family of highly fluorescent anthracycline antibiotics produced by several Streptomyces species, first reported in 1967 and later...
Cytochalasin J is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, which give rise to pronounced...
Apoptolidin, originally isolated from a Nocardiopsis sp., induces apoptotic cell death in rat glial cells transformed with the adenovirus E1A oncogene (IC50 = 11 ng/ml). Apoptolidin is among the most...
Epiequisetin is a minor isomer of equisetin, a potent inhibitor of HIV-integrase produced by a number of species of Fusarium. Chemically, equisetin equilibrates with epiequisetin. Although found to...
Cercosporamide was originally identified as a host-selective phytotoxin and broad spectrum antifungal agent isolated from Cercosporidium henningsii.Cercosporamide is soluble in ethanol, methanol, DMF...
Dihydrocyclosporin A is co-metabolite of Cyclosporin A. Dihydrocyclosporin A has no immunosuppressant activity and has found use as a control to determine the role of Cyclosporin A in pharmacology,...
