Our products for cancer research include natural products, antibiotics, chemotherapeutic agents, anti-tumor agents, drug precursors, and immunosuppressants. There are hundreds of high quality compounds to choose from to further your discoveries.
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Bevacizumab is a recombinant humanized monoclonal antibody used in cancer research. Its development was based on the discovery of human vascular endothelial growth factor (VEGF), a protein that stimulates blood vessel growth. VEGF was...
Tetrahydrolipstatin (orlistat) is a semi-synthetic derivative of lipstatin, a metabolite isolated from Streptomyces toxytricini. Tetrahydrolipstatin is widely used for the treatment of obesity.Tetrahydrolipstatin is soluble in ethanol, methanol, DMF and...
Siomycin is a macrocyclic thiopeptide antibiotic with potent and selective antibacterial activity first isolated from the fermentation product of Streptomyces sioyaensis by Nishimura in 1959. This member of the thiostrepton family is a potent inhibitor...
Tamoxifen is a compound used in breast cancer research and estrogen-related gynecomastia. It is a selective estrogen receptor modulator (SERM) and reduces growth of breast cancer cells, aling with its metabolite 4-hydroxytamoxifen. This member of...
Terrein is a polar, substituted dihydrocyclopentenone first reported by Raistrick and colleagues in the 1930s and subsequently found in a number of Aspergillus and Penicillium species.Terrein is soluble in ethanol, methanol, DMF and DMSO.Mechanism of...
Trinactin is a member of the macrotetrolide complex produced by a range of Streptomyces sp.. Early literature reported that trinactin was a monovalent cation ionophore with high selectivity for ammonium and potassium. Trinactin has not previously been...
Cefpirome Sulfate Solubilized is a mixture of Cefpirome Sulfate with anhydrous sodium carbonate that is used to stabilize the pH in aqueous solution. Cefpirome Sulfate is a semisynthetic, broad-spectrum, fourth generation cephalosporin antibiotic...
TS155-2 is a macrocyclic lactone related to hygrolidin but produced by a different Streptomyces species. With the exception of the original patent suggesting hypotensive, anti-platelet, anti-ischaemic and anti-inflammatory activity, no literature...
UK-1 is an unusual bis-benzoxazole metabolite isolated from a species of Streptomyces. UK-1 exhibits good antitumor activity but is devoid of antimicrobial activity.Mechanism of ActionUK-1 acts as a magnesium ion-dependent DNA binding agent and inhibitor...
Umirolimus is a semi-synthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group, providing one of most hydrophobic tacrolimus analogues. Umirolimus has been targeted for use in stents and medical devices to...
Valinomycin is a hydrophobic cyclodepsipeptide with potent antitumor activity. Valinomycin is a highly selective potassium ionophore and this action leads to a diverse range of profound cell membrane effects. More recently, valinomycin has found...
Nicotinamide (Vitamin B3), USP is water-soluble amide form of Nicotinic acid. It is a poly (ADP-ribose) polymerase (PARP) inhibitor, involved in regulation of many cellular processes. It was discovered between 1935 and 1937. ...