Our products for cancer research include natural products, antibiotics, chemotherapeutic agents, anti-tumor agents, drug precursors, and immunosuppressants. There are hundreds of high quality compounds to choose from to further your discoveries.
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Mizoribine is an imidazole nucleoside which acts as an immunosuppressant by inhibiting lymphocyte proliferation. Mizoribine is freely soluble in water (20 mg/mL).Mechanism of ActionMizoribine inhibits inosine monophosphate synthetase and guanosine...
Carboplatin, a cisplatin analog, is a platinum-based antineoplastic chemotherapeutic agent that has been used in cancer research including in vitro studies on lung, neck, breast, and cervical cancers. It was co-developed by Bristol Myers Squibb and the...
Conglobatin is a unique dimeric macrolide antibiotic derived from ionomycin, an ionophore produced by Streptomyces conglobatus. Conglobatin is soluble in ethanol, methanol, and DMSO.Mechanism of ActionMacrolide antibiotics inhibit bacterial growth by...
Herbimcyin is a sparingly soluble benzoquinone anti-tumor agent which interacts with the stress-induced chaperone protein Hsp90 (heat shock protein 90).Mechanism of ActionHerbimycin A binds specifically to the heat shock protein Hsp90 and to its...
FK-506, also known as Tacrolimus, is a macrolide immunosuppressive drug commonly used post-transplant to reduce graft rejection. FK-506 is insoluble in aqueous solution. This product is considered a dangerous good. Quantities above 1 g may be subject to...
Mitoxantrone Dihydrochloride is used for cancer research as a chemotherapeutic for leukemias and solid tumors. It has immunosuppressive activity and inhibits proliferation of lymphocytes and induces apoptosis of antigen-presenting T-cells...
Amygdalin is a cyanide-containing diglucoside derived from bitter almonds (Prunus dulcis) and apricot pits and is structurally related to Vitamin B17 but it is not a vitamin. The monoglucoside prunasin is the precursor to Amygdalin. In the...
Erlotinib hydrochloride is a drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer. It is a tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).Mechanism of ActionErlotinib is...
Cyclosporin H, EvoPure is a hydroxylated metabolite of Cyclosporin A. Cyclosporin H (M-1) and other Cyclosporin metabolites have been found to have lower (<10%) immunosuppressant activity than Cyclosporin A. Cyclosporin H has been...
Cyclosporin A, EvoPure is a neutral, cyclic oligopeptide with immunosuppressive activity. Cyclosporin A has the most potent immunosuppressive activity of the metabolites (Cyclosporin B, C, D, E, and H). Cyclosporin A has been used to prevent...
Cyclosporin D, EvoPure is a hydroxylated metabolite of Cyclosporin A. Cyclosporin D and other Cyclosporin metabolites have been found to have lower (<10%) immunosuppressant activity than Cyclosporin A. Cyclosporin D has been found to...
Cyclosporin C, EvoPure is a hydroxylated metabolite of Cyclosporin A. Cyclosporin C has similar immunosuppressant activity, but lower nephrotoxicity than Cyclosporin A. Cyclosporin C also has antimycotic properties. EvoPure® products have...
