Antitumor

Sulfasalazine

Sulfasalazine is a synthetic salicylic acid derivative and sulfonamide which can act as an antirhematic and gastrointestinal agent. It is formulated as a prodrug, and is metabolized into active metabolites sulfapyridine and mesalazine (5-aminosalicylic...

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Pitavastatin Calcium

Pitavastatin Calcium is the calcium salt formulation of Pitavastatin, a lipophilic statin that  inhibits cholesterol synthesis and displays cardioprotective properties. Pitavastatin is often combined with zoledronic acid for oncology applications...

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Podophyllotoxin

Podophyllotoxin, a natural, non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum species, was first isolated in 1880. Serving as a model for antii-tumor properties, Podophyllotoxin has been used to inhibit the growth of various...

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Aspulvinone O

Aspulvinone O is a biprenylated butyrolactone isolated from a strain of Paecilomyces by Chinese researchers in 2015.Aspulvinone O is a member of the larger aspulvinone family of secondary metabolites originally isolated from Aspergillusterreus by Seto...

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Asperfuran

Asperfuran is a dihydrobenzofuran produced by Aspergillus and cold tolerant Penicillium species. Asperfuran has antifungal, cytotoxic and weak chitin synthase activity. Molecular Formula  C13H14O3   References Frisvad J.C. et al...

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Byssochlamic Acid

Byssochlamic Acid is a nonadride mycotoxin first isolated from Byssochlamiys fulva by Raistrick and Smith at the Univeristy of London, UK in 1933. Byssochlamic Acid is closely related to the mycotoxins rubratoxin B, produced by Penicillium rubrum, and...

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Butyrolactone V

Butyrolactone V is a saturated dibenzylbutyrolactone lignan isolated from a strain of Aspergillus by Lin and collaborators,Xiamen University, China in 2009. Butyrolactone V is moderately active against the parasites, Plasmodium falciparum,Leishmania...

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IT-143A

IT-143-A is a rare, higher homolog of the piericidin class isolated from a Streptomyces sp. by Taiho Pharmaceuticals incollaboration with Chinese researchers in 1996. IT-143-A is active against the fungus, Aspergillus fumigatus, and the Gram-positive...

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IT-143B

IT-143B is a rare, higher homolog of the piericidin class isolated from a Streptomyces sp. by Taiho Pharmaceuticals incollaboration with Chinese researchers in 1996. IT-143B is active against the fungus, Aspergillus fumigatus, and the Gram-positive...

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Limonin

Limonin is a highly oxygenated terpenoid which forms the core structure of the citrus limonoid metabolites found mostly in the seeds, fruits and peel tissues of citrus. Limonin was first isolated over 175 years ago. In Australia, Limonin was isolated...

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Lupeol

Lupeol is a pentacyclic lupane triterpene produced by various fruits, vegetables and other plants, first isolated in 1898 and published in 1907. Lupeol is reported to have very diverse biological effects, including anti-inflammatory, anti-diabetic,...

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Norstictic Acid

Norstictic acid was first reported in 1934 as a metabolite produced by the lichen, Lobaria pulmonaria, along with two relatedcompounds. Norstictic acid has antioxidant, antimicrobial and antitumor activities. Norstictic acid treatment...

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