Lasalocid Sodium is the salt form of Lasalocid, a carboxylic polyether ionophore. The compound has anticancer properties and antibacterial activity. Lasalocid is isolated from Streptomyces...
Asukamycin is an unusual trienoic acid amide metabolite produced by Streptomyces nodosus, reported by Omura and colleagues at the Kitasato Institute, Japan, in 1976. Asukamycin belongs to the...
Melittin is the principal toxic component of honey bee venom from Apis mellifera, making up 50% of its dry weight. It is a 26 residue long antimicrobial peptide has an α-helical conformation, and...
Actinopyrone A is a gamma-pyrone compound isolated from a Streptomyces sp. It shows selective (>106 fold) and potent (MIC=0.0001 µg/ml) activity against Helicobacter pylori, the principal cause of...
Ansatrienin A, isolated from a Streptomyces sp., is closely related to the cytotrienins and trienomycins. It displays potent activity against tumor cell lines and inhibits osteoclastic bone...
Ansatrienin B, also known as Mycotrienin II and Antibiotic T 23II, was isolated from a Streptomyces sp.. Closely related to the cytotrienins and trienomycins, it displays potent activity against...
Acriflavine Hydrochloride (syn: Acriflavine HCl) is the hydrochloride salt of Acriflavine, a mixture of 3,6-diamino-10-methylacridium (acriflavin) and 3,6-diaminoacridine (proflavin). It was...
Mebendazole is a broad-spectrum benzimidazole and anti-helminthic used as a treatment for roundworms. More recently it has been investigated as an anti-cancer agent, showing promise in vitro and in...
Geninthiocin is a thiopeptide antibiotic isolated from a Streptomyces sp. Geninthiocin displays a 10-fold selectivity for bacteria over mammalian cells lines, whereas the related dedialanyl...
Aureothin, an unusual pyranone metabolite, has broad biological actions including antitumor, antimicrobial and insecticidal activities. More recently, aureothin has been shown to be a potent...
Butyrolactone I is one of a family of three butyrolactones isolated from Aspergillus fumigatus, first reported in 1983. Butyrolactone I is a selective inhibitor of cyclin-dependent kinases...
Kigamicin C was discovered by an anti-austerity strategy, targeting cancer cells' tolerance to starvation. It selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower...
