Aspyrone is a chiral dihydropyranone with nematocidal activity isolated from Aspergillus melleus by researchers at ICI in 1967. Aspyrone has antifungal and antibacterial activity and is more active...
Aspergillin PZ is an isoindole metabolite isolated from Aspergillus awarori by activity-guided fractionation and purification. Aspergillin PZ adversely affects the hyphae and spores of P. oryzae, a...
Ascochin is isolated from the endophytic fungus, Ascochyta species with antifungal, antibacterial and phytotoxic properties. Molecular Formula C1
Artemisinin is a sesquiterpene lactone isolated from the aerial parts of Artemisia annua L.. Artemisin is best known for its activity against the malaria parasite including resistant strains, but...
Aranciamycin A is an anthracycline bearing a methyl-L-rhamnose sugar in the 2-O position. Aranciamycin A has antitumor and Gram positive antibiotic activity and is a potent inhibitor of Clostridium...
Aquastatin A, produced by Fusarium sp., is an inhibitor of mammalian adenosine triphosphatases with an IC50 of 7.1 µM against Na+/K+-ATPase 6.2 µM against H+/K+-ATPase. Aquastatin A is a potent...
Apramycin is a structurally unique broad-spectrum aminoglycoside with a bicyclic sugar moiety and a monosubstituted deoxystreptamineactive. Apramycin inhibits the translocation step of bacterial...
Ansamitocins, a new group of ansamycin antibiotics with potent antitumor activity, were first reported in the journal Nature in 1977 by researchers from Takeda Chemical Industries. Anisomitocin P3 is...
Anandamide is an endogenous ligand for the cannabinoid receptor. Anandamide activates receptor-mediated signal transduction and stimulates arachidonic acid and intracellular calcium release in both...
Anagyrine is a teratogenic quinolizidine alkaloid found in Lupinus sp. which undergoes metabolism to a piperidine that causes crooked calf syndrome. Anagyrine, but not lupanine or sparteine, directly...
Amycolatopsin C is a glycosylated polyketide isolated by Microbial Screening Technologies from Amycolotopsis sp.. The amycolatopsins are closely related to the ammocidins and apoptolidins...
Amycolatopsin B is a glycosylated polyketide isolated by Microbial Screening Technologies. The amycolatopsins are closely related to the ammocidins and apoptolidins. Amycolatopsin A and C, bearing a...