Heronamide C is an unusual polyene macrocyclic lactam containing two isolated tetraene and triene chromophores. Heronamide C induces a unique reversible vacuolisation of mammalian tumor cells...
Diacetylphloroglucinol (DAPG) is a small molecular weight phenolic metabolite belonging to the phloroglucinol (1,3,5- trihydroxybenzene) family produced by bacteria, including Pseudomonas strains...
Demethoxyviridiol is a fungal metabolite belonging to the wortmannin and viridin classes. An inhibitor of phosphatidylinositol 3-kinase, demethoxyviridiol affects phospholipid signalling and...
Cryptotanshinone is one of several bioactive tanshinones extracted from the Chinese medicinal herb, Salvia mitiorrhiza. It exhibits a variety of bioactivity including antibacterial, antioxidant and...
Davercin (erythromycin A cyclic 11,12-carbonate) is a first generation semi-synthetic erythromycin. Davercin is prepared by coupling the 11- and 12-OH groups to form a cyclic carbonate. This simple...
Cyclopiazonic acid is a tremorigenic indole produced by several species of Aspergillus and Penicillium. Cyclopiazonic acid is a highly specific inhibitor of calcium ATPase of sarcoplasmic reticulum,...
Pristinamycin is a streptogramin antibiotic. It is a mixture of Pristinamycin IA (a macrolide) and Pristinamycin IIA (streptogramin A), a depsipeptide). PI and PII are structurally unrelated but...
Virginiamycin B is a depsipeptide antibiotic co-produced with ostreogrycin A, together used as a synergistic mixture. Virginiamycin B, also known as ostreogrycin B and streptogramin B among other...
Teicoplanin A2-2 is a major analog of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. They possess potent antibiotic activity against Gram-positive bacteria, including MRSA...
Tetromycin A is an unusual tetronic acid, structurally related to kijanimicin, chlorothricin, saccharocarcin, tetrocarcin and versipelostatin. Tetromycin A has pronounced activity against antibiotic...
Virginiamycin is a streptogramin, and a mixture of Virginiamycin M1 and Virginiamycin S1. The commercial mixture is 75% Virginiamycin M1 and 25 % Virginiamycin S1, along with less abundant S analogs...
Viridicatumtoxin is a tetracycline-like metabolite produced by several species of Penicillium, first isolated in 1976 as a mycotoxin. Initial testing revealed that viridicatumtoxin caused myocardial...
