Bicyclomycin is a polar metabolite first isolated from Streptomyces sapporonensis in 1972. The selective Gram negative profile of bicyclomycin is rare among Streptomyces metabolites.Bicyclomycin is...
Azidamfenicol is a semi-synthetic chloramphenicol in which the nitro moiety is replaced with a methylsulphone and the dichloroacetamide is replaced with azidoacetamide, first synthesised at Bayer in...
Bicyclomycin is a polar metabolite first isolated from Streptomyces sapporonensis in 1972, with activity against Gram negative bacteria. The selective Gram negative profile of bicyclomycin is rare...
Bromamphenicol is a semi-synthetic chloramphenicol analogue first reported in 1950, in which the dichloroacetamide is replaced with dibromoacetamide. Bromamphenicol possesses weak antibiotic activity...
Tyrocidine is a family of eight cationic cyclic decapeptides produced by Bacillus brevis, a soil microorganism. Tyrocidine was first reported by Dubos in 1941 and was the first commercially...
Usnic acid is a major metabolite from a number of lichen and fungal species and is perhaps one of the longest known microbial metabolites, first isolated in 1844. Usnic acid exhibits a broad range of...
Valnemulin is a semi-synthetic pleuromutilin prepared by sequential reaction of pleuromutilin tosylate with 2-amino-1,1-dimethylethylthiol, coupling the free amine with a protected valine and then...
Dichlorophen is a tenicide, most often used in the treatment of small mammals. Antifungal, antibacterial and herbicidal activity has also been reported. While dichlorophen has low toxicity to...
Toyocamycin is a pyrrolopyrimidine nucleoside isolated from Streptomyces toyocaensis in 1956. Toyocamycin, like other members of pyrrolopyrimidine class, is an adenosine nucleotide antimetabolite...
Miltefosine is primarily used as an antileishmanial drug with demonstrated activity against other parasites, cancer cells, and pathogenic bacteria and fungi.Mechanism of ActionSeveral potential...
Embelin is a benzoquinone derivative from the Japanese Ardisia herb. It is a cell-permeable, small-molecule inhibitor of apoptosis regulator proteins. It is a promising start to a new class of...
Magainin I is a 23 residue long antimicrobial peptide originally discovered in the skin of Xenopus laevis. It has shown broad-spectrum antibiotic activity, particularly of E. coli, and antifungal...
