Antimicrobials

Corynecin II

Corynecin II is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin II is active against Gram positive and Gram negative bacteria. Although less...

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Corynecin IV

Corynecin IV is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin IV is active against Gram positive and Gram negative bacteria. Although less...

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L-681217

L-681217 is a glycolipid-type antibiotic related to the efrotomycin class, isolated from a Streptomyces sp.. L 681,217 shows broad spectrum antibiotic activity against Gram positive and Gram negative bacteria.L-681217 is soluble in ethanol, methanol, DMF...

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Gamithromycin

Gamithromycin is a semi-synthetic macrocyclic lactone belonging to the azalide class derived from erthyromycin, typified by azithromycin. The synthesis of gamithromycin involves a ring expansion using a Beckmann rearrangement to produce the 15-membered...

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Corynecin V

Corynecin V is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin V is active against Gram positive and Gram negative bacteria. Although less...

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Magainin II

Magainin II is an antimicrobial peptide originally isolated from Xenopus laevis, with excellent antibiotic activity across a broad-spectrum. It has also demonstrated antifungal activity in vitro and anticancer activity in vitro and in a mouse model...

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Erythromycylamine

Erythromycylamine is a semi-synthetic analogue of erythromycin prepared by reduction of erythromycin oxime. Erythromycylamine is a potent antibiotic, however the introduction of the amino- moiety increases the compound's polarity and is disadvantageous...

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Deoxyenterocin

Deoxyenterocin is a minor co-metabolite of enterocin produced by several species of Streptomyces. Interestingly, deoxyenterocin was first isolated from an ascidian. Like enterocin, deoxyenterocin exhibits activity against both Gram positive and Gram...

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Enterocin

Enterocin is a potent antibiotic with broad spectrum activity against Gram positive and Gram negative bacteria.The genetics of enterocin biosynthesis have been extensively investigated. Enterocin acts synergistically with streptomycin and...

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Desotamide

The cyclic hexapeptide, desotamide, was first isolated from a Streptomyces sp. found to produce salinamide A, an inhibitor of bacterial RNA polymerase. Little is known of desotamide's intrinsic activity or potency.Desotamide is soluble in ethanol,...

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Dihydropleuromutilin

Dihydropleuromutilin is a semi-synthetic pleuromutilin formed by selective reduction of the ethene to ethyl. Dihydropleuromutilin exhibits comparable antibiotic potency to pleuromutilin. Extensive studies have been undertaken on semi-synthetic...

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Moenomycin

Moenomycin complex is a mixture of five major components, A, A12, C1, C3 and C4, isolated from several strains of Streptomyces in the 1960s. Moenomycins are high molecular weight phosphoglycolipids with potent antibiotic activity used in animal health...

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