Antimicrobials

Citrinin

Citrinin is a quinonemethine mycotoxin produced by diverse fungi including Aspergillus and Penicillium. Citrinin has been extensively investigated and is a potent nephrotoxin with hepatoxic and teratogenic activity. Citrinin is the causative agent of...

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Corynecin I

Corynecin I is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin I is active against Gram positive and Gram negative bacteria. Although less...

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Corynecin II

Corynecin II is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin II is active against Gram positive and Gram negative bacteria. Although less...

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Corynecin IV

Corynecin IV is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin IV is active against Gram positive and Gram negative bacteria. Although less...

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L-681217

L-681217 is a glycolipid-type antibiotic related to the efrotomycin class, isolated from a Streptomyces sp.. L 681,217 shows broad spectrum antibiotic activity against Gram positive and Gram negative bacteria.L-681217 is soluble in ethanol, methanol, DMF...

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Gamithromycin

Gamithromycin is a semi-synthetic macrocyclic lactone belonging to the azalide class derived from erthyromycin, typified by azithromycin. The synthesis of gamithromycin involves a ring expansion using a Beckmann rearrangement to produce the 15-membered...

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Corynecin V

Corynecin V is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin V is active against Gram positive and Gram negative bacteria. Although less...

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Magainin II

Magainin II is an antimicrobial peptide originally isolated from Xenopus laevis, with excellent antibiotic activity across a broad-spectrum. It has also demonstrated antifungal activity in vitro and anticancer activity in vitro and in a mouse model...

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Erythromycylamine

Erythromycylamine is a semi-synthetic analogue of erythromycin prepared by reduction of erythromycin oxime. Erythromycylamine is a potent antibiotic, however the introduction of the amino- moiety increases the compound's polarity and is disadvantageous...

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Deoxyenterocin

Deoxyenterocin is a minor co-metabolite of enterocin produced by several species of Streptomyces. Interestingly, deoxyenterocin was first isolated from an ascidian. Like enterocin, deoxyenterocin exhibits activity against both Gram positive and Gram...

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Enterocin

Enterocin is a potent antibiotic with broad spectrum activity against Gram positive and Gram negative bacteria.The genetics of enterocin biosynthesis have been extensively investigated. Enterocin acts synergistically with streptomycin and...

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Desotamide

The cyclic hexapeptide, desotamide, was first isolated from a Streptomyces sp. found to produce salinamide A, an inhibitor of bacterial RNA polymerase. Little is known of desotamide's intrinsic activity or potency.Desotamide is soluble in ethanol,...

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