Concanamycin B is a macrocyclic lactone originally isolated from Streptomyces diastatochromogenes in 1982 as a potent inhibitor of the proliferation of mouse splenic lymphocytes stimulated by...
Carbadox is a broad spectrum antibiotic commonly used as a in-feed additive for swine production to improve feed efficiency and to prevent dysentery and swine enteritis. Carbadox has been shown to...
Kazusamycin A is a minor member of the Leptomycin complex isolated from some Streptomyces species. It is a hydroxylated analog of Leptomycin B, a nuclear export inhibitor. It is similar to...
PC-766B is a 16-membered macrolide antibiotic produced by Nocardia brasiliensis, reported by researchers at Sumitomo in 1993. Structurally, PC-766B is a member of bafilomycin class, featuring a rare...
Puromycin is an aminonucleoside antibiotic with anti-trypanosomal and antineoplastic properties. It was isolated from Streptomyces alboniger in the 1950s. Puromycin is used in cell biology to select...
Oleandomycin is a 16-membered macrocyclic lactone, discovered in the 1950s, with broad-spectrum antibacterial activity. It has activity profile similar to erythromycin and penicillin. It is...
Kijanimicin is a tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin. Like the tetrocarcins, kijanimicin contains an unusual nitroaminoglycoside. Kijanimicin is a...
Albofungin is a polyaromatic heterocycle containing a rare N-aminoamide, isolated from a Streptomyces species in Russia in 1959. Albofungin exhibits a broad biological profile with antibiotic,...
Doxorubicin (syn: Adriamycin) is the most extensively studied of a family of highly fluorescent anthracycline antibiotics produced by several Streptomyces species, first reported in 1967 and later...
Cytochalasin J is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, which give rise to pronounced...
Nemadectin is a natural substance with broad-spectrum endectocidal, nematicidal and insecticidal activity. It is a macrocyclic lactone that is structurally similar to milbemycin and avermectin...
Epiequisetin is a minor isomer of equisetin, a potent inhibitor of HIV-integrase produced by a number of species of Fusarium. Chemically, equisetin equilibrates with epiequisetin. Although found to...
