Quinaldopeptin

Quinaldopeptin is a symmetrical, cyclic decapeptide from an Amycolatopsis sp. that is a bis-intercalator of DNA, exhibiting strong in vitro antimicrobial and cytotoxic activity. Quinaldopeptin significantly prolongs the survival time of mice inoculated...

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Cytochalasin A

Cytochalasin A is one of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, giving rise to pronounced morphogenic activity in animals and plants. Despite the...

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Methacycline Hydrochloride

Methacycline Hydrochloride is a member of the tetracycline antibiotics and is more active against Gram-negative and Gram-positive bacteria than tetracycline and demethylchlortetracycline. Application Methacycline HCl can be used as a synthetic...

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Terrecyclic Acid

Terrecyclic acid is a tricyclic sesquiterpene antibiotic produced by Aspergillus terreus, first reported by researchers at the Universities of Osaka and Tokyo in 1982. Terrecyclic acid A had a wide antimicrobial spectrum of rather weak activities...

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Leucinostatin A

Leucinostatin A is the major component of an atypical nonapeptide complex produced by Paecilomyces lilacinus, first reported in 1973. Leucinostatins display broad bioactivity against Gram-positive bacteria, fungi, plants and tumor cell lines...

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Cytochalasin C

Cytochalasin C is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, resulting in pronounced morphogenic changes in animals and plants. The cytochalasins act by...

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Chrysomycin A

Chrysomycin A is the major analogue in a complex of C-glycoside antitumor actives isolated from Streptomyces. Chrysomycin A, with a vinyl group in the 8-position, is the most potent analogue of the complex, and is thought to act as an inhibitor of the...

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Aphidicolin

Aphidicolin is a tetracyclic diterpene antibiotic isolated from fungi, notably Cephalosporium, Nigrospora, Harziella and Phoma. Aphidicolin has antibiotic, antiviral and antimitotic properties, blocking the cell cycle at early S-phase. This property has...

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Cytochalasin D

Cytochalasin D is the most studied of the cytochalasins. Like most of the members of this mycotoxin class, cytochalasin D exhibits potent inhibition of actin filament function leading to cell death by apoptosis. This led to early investigation of the...

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Sulbactam Sodium

Sulbactam Sodium is an irreversible inhibitor of several bacterial penicillinases and cephalosporinases. In the presence of low concentrations of sulbactam, ampicillin and other β-lactams readily inhibit the growth of a variety of resistant bacteria...

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Bactenecin

Bactenecin is a cyclic, 12 amino acid antimicrobial peptide (AMP) with antibacterial activity against Gram-negative and some Gram-positive bacteria. Mechanism of ActionBactenecin inhibits protein synthesis by binding to bacterial ribosomes...

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Alizarin

Alizarin (1,2-dihydroxyanthraquinone) is a red dye wilth mild antibacterial activity. Alizarin has been found to inhibit biofilm formation by three Staphylococcus aureus strains and a Staphylococcus epidermidis strain. Mechanism of ActionAlizarin...

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