Antimicrobials

Clarithromycin, USP

Clarithromycin, USP is a macrolide antibiotic that is derivative of Erythromycin.  This compound is both a substrate and inhibitor of CYP3A4.   Clarithromycin has anti-cancer properties.  Clarithromycin-related compounds are also...

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Elaiophylin

Elaiophylin is a highly characteristic metabolite produced by Streptomyces hygroscopicus. Elaiophylin inhibits testosterone 5-reductase and is synergistic with its co-metabolite, rapamycin, as an antifungal. Elaiophylin also has anthelmintic and...

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Sulfamerazine Sodium

Sulfamerazine is a bacteriostatic sulfonamide antibiotic. TOKU-E offers two forms of Sulfamerazine: Sulfamerazine (S033) and Sulfamerazine sodium (S059).Mechanism of ActionLike most sulfonamides, Sulfamerazine sodium inhibits folic acid synthesis by...

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Cetrimide

Cetrimide is a bactericidal cationic surfactant used against Gram-positive bacteria.  It is commonly used in selective medium to isolate Pseudomonas aeruginosa. Cetrimide is an active ingredient in Cetavlon, a detergent used in plant surface...

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Ribostamycin Sulfate

Ribostamycin is an aminoglycoside antibiotic and is freely soluble in aqueous solution at 88.7 mg/mL. Ribostamycin is an aminoglycoside-aminocyclitol antibiotic isolated from Streptomyces ribosidificus, originally from a soil sample in Japan.  It is...

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Oxacillin Sodium, USP

Oxacillin Sodium, USP is the sodium salt of Oxacillin, semisynthetic penicillinase-resistant and acid-stable antibiotic of the penicillin class.  It is a narrow-spectrum β-lactam antibiotic primarily used against Gram-positive organisms. ...

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Sisomicin Sulfate

Sisomicin sulfate is a soluble broad-spectrum aminoglycoside antibiotic, and a dihydro analog of gentamicin C1a sulfate, Evopure.  Sisomicin was first isolated in 1970 from Micromonopora inyoensis, a novel strain at the time, that was...

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Micronomicin Sulfate

Micronomicin Sulfate is the sulfate salt of Micronomicin, a natural aminoglycoside, broad-spectrum antibiotic discovered and developed by Kyowa Hakko Kogyo Co.  The structure was determined as 6’-N-methylgentamicin C1a, and it is similar to...

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Ofloxacin

Ofloxacin is a synthetic, broad-spectrum, second-generation fluoroquinolone antibiotic that is an analog of nalidixic acid. It was developed by Daiichi Seiyaku to be resistant to metabolic oxidation in the liver and inhibits the supercoiling activity of...

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Sulfamethazine Sodium

Sulfamethazine sodium, also known as sulfadimidine sodium, is a bacteriostatic heterocyclic sulfonamide antibiotic that was first synthesized from sulfanilamide at Temple University in Philadelphia by William Caldwell in 1942.  Sulfamethazine has...

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Netilmicin Sulfate

Netilmicin Sulfate is the sulfate salt form of Netilmicin, a semisynthetic, broad-spectrum aminoglycoside antibiotic. It is a 1-N-ethyl derivative of the natural antibiotic sisomycin produced by fermentation of Micromonospora inyoensis that has a...

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Nisin

Nisin (Nisin A) is a natural bacteriocin polypeptide antibiotic known as a lantibiotic. It is a 34-amino acid polycyclic antibacterial peptide.  It was isolated in the late 1930s from Lactococcus lactis.  Nisin A and Nisin Z are two...

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