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Antibacterials

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  • 3-Hydroxy-L-tyrosine methyl ester

    3-Hydroxy-L-tyrosine methyl ester

    3-Hydroxy-L-tyrosine methyl ester (melevodopa, L-dopa methyl ester) is a prodrug of levodopa used for the treatment of Parkinson’s disease. L-​DOPA methyl ester is a potent competitive antagonist for the action of L-​DOPA...

  • 3-Acetyldeoxynivalenol

    3-Acetyldeoxynivalenol

    3-Acetyldeoxynivalenol is a trichothecene mycotoxin produced by Fusarium species, exhibiting dose-dependent reduction of lymphocyte proliferation in mitogen-induced blastogenesis, albeit less potently than deoxynivalenol. In a comparative study of...

  • 2-Benzoxazolinone

    2-Benzoxazolinone

    2-Benzoxazolinone is a metabolite produced by rye (Secale cereale) that inhibits germination and growth and causing oxidative damage.  2-Benzoxazolinone has diverse pharmacological activities including antinociception, anti-inflammatory,...

  • 1-Acetylchloramphenicol

    1-Acetylchloramphenicol

    1-Acetylchloramphenicol is an isomer of chloramphenicol acetate, a naturally-occurring co-metabolite of chloramphenicol in Streptomyces venezuelae albeit with significantly lower potency. Chloramphenicol acetate is the major product of chloramphenicol...

  • 19-O-Acetylchaetoglobosin A

    19-O-Acetylchaetoglobosin A

    19-O-Acetylchaetoglobosin is a phytotoxin isolated from Acremonium and other fungal species. 19-O-Acetylchaetoglobosin A is also produced by the fungi Ijuhya vitellina sp. nov. which parasitises a cereal cyst nematode. Molecular...

  • 17-Dimethylaminoethylamino-17-demethoxygeldanamycin

    17-Dimethylaminoethylamino-17-demethoxygeldanamycin

    17-Dimethylaminoethylamino-17-demethoxygeldanamycin (DMAG, alvespimycin) is a semi-synthetic derivative of the benzoquinone ansamycin antibiotic isolated from Streptomyces hygroscopicus in which the methoxy group attached to...

  • 17-Allylamino-17-demethoxygeldanamycin

    17-Allylamino-17-demethoxygeldanamycin

    17-allylamino-17-demethoxygeldanamycin (17-AAG), a semi-synthetic derivative of geldanamycin, is a potent antitumor agent that acts by binding to the 90-kDa heat-shock protein (Hsp90) essential to maintain the conformation, stability, activity and...

  • 15-Acetyldeoxynivalenol

    15-Acetyldeoxynivalenol

    15-Acetyldeoxynivalenol is a trichothecene mycotoxin produced by Fusarium sp. infecting cereals and grains and posing a health risk to humans and livestock. 15-Acetyldeoxynivalenol has lower acute oral toxicity than deoxynivalenol in mice. In a...

  • 6,7-Dimethoxy-2,2-dimethyl-3-chromene

    6,7-Dimethoxy-2,2-dimethyl-3-chromene

    6,​7-​dimethoxy-​2,​2-​dimethyl-​3-​chromene (ageratochromene) is a metabolite of some plants including Ageratum spp. and Verbesina spp. Its synthesis was reported in 1958. 6,​7-​dimethoxy-​2,​2-​dimethyl-​3-​chromene induces premature ecdysis in...

  • 15-Acetoxyscirpenol

    15-Acetoxyscirpenol

    15-Acetoxyscirpenol is a trichothecene mycotoxin produced by Fusarium sp. infecting cereals and grains and posing a health risk to humans and livestock. 15-Acetoxyscirpenol is also formed by biodegradation of diacetoxyscirpenol. 15-Acetoxyscirpenol...

  • Kanamycin B, EvoPure

    Kanamycin B, EvoPure

    Kanamycin B, EvoPure is a highly purified form of Kanamycin B. Kanamycin B is a minor component of the Kanamycin complex, along with C, with Kanamycin A being the major component. Kanamycn B is a close structural analog of DAA2 and it has an unmethylated...

  • Ceftolozane Sulfate, Stabilized with Arginine

    Ceftolozane Sulfate, Stabilized with Arginine

    Ceftolozane Sulfate, Stabilized with Arginine is a broad-spectrum, fifth-generation cephalosporin with bactericidal activity. It can be used in biopharma research for impurity profiling and chemical stability testing. It can also be used for penicillin...

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