Aclarubicin (aclacinomycin A) is an anthracycline and topoisomerase II inhibitor that has been clinically tested against haematologic and solid tumors. Aclarubicin stabilizes topoisomerase I cleavage...
Acivicin is a chlorinated amino acid originally isolated from Streptomyces sviceus that inhibits glutmate metabolism. It has antifungal, antitumor and antileishmanial properties. Acivicin...
Acetomycin, a γ-butyrolactone isolated from Streptomyces ramulosus, was first reported in 1958 by Ettlinger et al. at ETH Zurich. Acetomycin is potently active in vitro against HCT-8 human colon...
Acadesine was originally identified as a metabolite of Bacillus species and was shown to accumulate in the culture medium of E. coli under sulphonamide stasis. Acadesine is an adenosine-regulating...
Floramultine was first isolated from Kreysigia multiflora, a member of the Liliacaeae family, in 1960 by Badger and Bradbury, University of Adelaide, Australia. The absolute configuration of...
5-Methoxycanthinone is a β-carboline first isolated from the Australian Rutaceae Pentaceras Australis Hook by Price and co-workers at the CSIRO, Australia in 1952. 5-Methoxycanthinone is a modest...
4’-Acetylchrysomycin B and its co-metabolite, 4’-acetylchrysomycin A, were isolated during a screen for antitumor agents. Acetylation of chyrsomycin B increase cytotoxicity. Acetylchyrsomycins are...
4'-Acetylchrysomycin C is a methylated analogue of 4'-acetylchrysomycin A. To date there are no reports of the biological activity of 4-acetylchrysomycin C in the literature. Molecular Formula
3-Hydroxy-L-tyrosine methyl ester (melevodopa, L-dopa methyl ester) is a prodrug of levodopa used for the treatment of Parkinson’s disease. L-DOPA methyl ester is a potent competitive antagonist for...
3-Acetyldeoxynivalenol is a trichothecene mycotoxin produced by Fusarium species, exhibiting dose-dependent reduction of lymphocyte proliferation in mitogen-induced blastogenesis, albeit less...
2-Benzoxazolinone is a metabolite produced by rye (Secale cereale) that inhibits germination and growth and causing oxidative damage. 2-Benzoxazolinone has diverse pharmacological activities...
1-Acetylchloramphenicol is an isomer of chloramphenicol acetate, a naturally-occurring co-metabolite of chloramphenicol in Streptomyces venezuelae albeit with significantly lower potency...
