SKU: D092  / 
    CAS Number: 171500-79-1

    Dalbavancin Hydrochloride

    €141,29 - €505,23
    Dalbavancin Hydrochloride
    • Detailed Description

      CAS Number: 171500-79-1

      Molecular Formula: C88H100Cl2N10O28 . HCl

      Molecular Weight: 1853.15

      Mechanism of Action: Dalbavancin HCl disrupts cell wall biosynthesis. It binds to the D-alanyl-D-alanyl residue on growing peptidoglycan chains and prevents transpeptidation. Unlike naturally occurring glycopeptides, Dalbavancin can dimerize and anchors itself in the bacterial membrane whcih improves stabilizationa nd increases its affinity for peptidoglycan.

      Storage Conditions: -20°C

    • Applications

      Spectrum: Gram-positive bacteria

      Microbiology Applications: Dalbavancin has more potent in vitro bactericidal activity than vancomycin or teicoplanin against many resistant organisms such as MRSA and Methicillin-resistant Staphylococcus epidermidis (MRSE). It is active in vitro against S. pneumonieae, S. pyogenes, vancomycin-Sensitive Enterococcus.

    • Specifications

      Form: Powder

      Appearance: Powder

      Source: Semi-synthetic

      Purity Level: 85% - 105% (anhydrous and free base basis)

    Dalbavancin is a second generation, semi-synthetic lipoglycopeptide antibiotic that is active against Gram-positive bacteria.  It was designed to improve upon the natural glycopeptides currently available (vancomycina and teicoplanin) and was launched in 2014.  It is used to combat the bacteria causing acute bacterial skin and skin structure infections.

    CAS Number: 171500-79-1

    Molecular Formula: C88H100Cl2N10O28 . HCl

    Molecular Weight: 1853.15

    Mechanism of Action: Dalbavancin HCl disrupts cell wall biosynthesis. It binds to the D-alanyl-D-alanyl residue on growing peptidoglycan chains and prevents transpeptidation. Unlike naturally occurring glycopeptides, Dalbavancin can dimerize and anchors itself in the bacterial membrane whcih improves stabilizationa nd increases its affinity for peptidoglycan.

    Storage Conditions: -20°C

    Spectrum: Gram-positive bacteria

    Microbiology Applications: Dalbavancin has more potent in vitro bactericidal activity than vancomycin or teicoplanin against many resistant organisms such as MRSA and Methicillin-resistant Staphylococcus epidermidis (MRSE). It is active in vitro against S. pneumonieae, S. pyogenes, vancomycin-Sensitive Enterococcus.

    Form: Powder

    Appearance: Powder

    Source: Semi-synthetic

    Purity Level: 85% - 105% (anhydrous and free base basis)