Isocyclosporin A is a rearranged degradation product formed by acid treatment of Cyclosporin A under aqueous and non-aqueous conditions. This rearrangement has been used as the basis of a HPLC fluorescence for quantifying Cyclosporin A. The pharmacology of Isocyclosporin A has received little attention.
Isocyclosporin A is soluble in ethanol, methanol, DMF or DMSO.