Bioactive small molecules are organic compounds that have a low molecular weight (900 daltons). Most pharmaceutical drugs are small molecules. Larger structures such as nucleic acids, proteins, and many polysaccharides are not small molecules.
Terpendole I is a polar analog of a rare family of indolediterpenes isolated from Albophoma yamanashiensis, first reported by Omura and colleagues at the Kitasato Institute, Japan in 1995. Terpendole...
Vobtusine is a dimeric indole alkaloid derived from the various species of Voacanga, indigenous to Africa, first reported in 1955. In the Pacific region, vobtusine was successfully isolated from the...
Voacangine is an indole alkaloid derived from various species of Voacanga, indigenous to Africa. In the Pacific region,voacangine was successfully isolated from Tabernaemontana aurantiaca (syn...
Voacamine is an indole alkaloid derived from members of the Voacanga species, indigenous to Africa. In the Pacific region,voacamine was successfully isolated from the small tree, Voacanga papuana,...
Levodropropizine has anti-allergic properties and inhibits the histamine receptor. It acts as a peripheral antitussive agent. Mechanism of Action Levodropropizine has affinity for H1-histaminic...
Xanthyletin, a dimethylpyranocoumarin structurally related to psoralen, is the active principal of Luvanga scandens widely used in Hindu medicine. Xanthyletin was isolated from the New Guinea tree,...
Emodepside is an anthelmintic, belonging to the cyclooctadepsipeptides class. It is effective against gastrointestinal nematodes. The starting material of Emodepside is a natural metabolite of the...
Cephapirin Sodium is the sodium salt form of Cephapirin, a broad-spectrum, beta-lactam antibiotic. It is a sem-synthetic, first-generation cephalosporin C with bactericidal activity. Cephapirin is a...
Drimendiol is the sesquiterpene dialcohol of polygodial, found in a number of plant species native to Australia and NewZealand. More recently, drimendiol was prepared from polygodial isolated from...
Levofloxacin Hydrochloride is the hydrochloride salt of Levofloxacin. It is a broad-spectrum fluoroquinolone antibiotic and the optical S-(-) isomer of Ofloxacin. The compound is a DNA gyrase...
2’-C-Methylcytidine (syn: 2CMC) is a viral replication inhibitor, shown to be active against multiple viruses including hepatitis C virus (HCV), inhibiting the HCV NS5B RNA polymerase. It is also...
Ceftiofur Hydrochloride is the hydrochloride salt of Ceftiofur, a broad-spectrum, third-generation β-lactamase resistant cephalosporin commonly used in veterinary research applications that was first...
