Our products for cancer research include natural products, antibiotics, chemotherapeutic agents, anti-tumor agents, drug precursors, and immunosuppressants. There are hundreds of high quality compounds to choose from to further your discoveries.
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Fumagillin is a polyene natural product and mycotoxin isolated from Aspergillus fumigatus in 1951 as a potent antiprotozoan for agents that cause amoebiasis. More recently, Fumagillin has been shown to inhibit endothelial cell proliferation and...
Valrubicin is a semisynthetic derivative of the antineoplastic anthracycline antibiotic doxorubicin. It is used for cancer research in models of bladder cancer. Mechanism of Action Valrubicin is converted into N-trifluoroacetyladriamycin, which...
Miconazole Nitrate is the nitrate salt of Miconazole, an imidazole antimycotic compound patented in 1968 (Janssen Pharmaceutica). It targets the fungi that cause tinea (ringworm) and athlete’s foot. It inhibits ergosterol synthesis, and...
1-Alaninechlamydocin is a cyclic tetrapeptide metabolite containing a single β-amino acid, which was isolated from a Tolypocladium sp. from the Great Lakes. It has anti-cancer properties due to the inhibition of histone deacetylase (HDAC)...
Diacetylcercosporin is a minor hydrophobic analogue of cercosporin produced by several species of the fungal genera, Cercospora and Septoria. Diacetylcercosporin has moderate in vitro activity against Leishmania and chloroquine-sensitive strains of...
Pyrrole-2-carboxylic acid is small amphoteric polar metabolite produced by many Streptomyces species, often co-produced with its dimer, pyrocoll. Pyrrole-2-carboxylic acid is an important dereplication standard in discovery, displaying a distinctive UV...
Streptonigrin is an unusual aminoquinone with broad biological activity against bacteria, fungi, nematodes, viruses and tumor cells. Streptonigrin acts as a bioreductive agent, highly dependent on interactions with metal ions, notably iron, and plays an...
Cercosporin (CGP049090) is a perylenequinone reported in 1957 as the causative agent of soy bean purple speck disease due to the fungal pathogen, Cercsopsorium kikuchii, which is widely found in species of Cercosporium. Cercosporin phytotoxicity is...
Ascochlorin is an antitumor fungal metabolite with antitumor and antiviral properties.Ascochlorin is soluble in ethanol, methanol, DMF and DMSO and has limited water solubility.Mechanism of ActionAscochlorin specifically inhibits matrix...
Trastuzumab is a recombinant humanized monoclonal antibody that is used in the treatment of cancer.This product comes in a liquid form with a protein content of >15 mg/mL.Mechanism of ActionHER2 is a receptor tyrosine kinase and epidermal growth...
Thiostrepton is a bactericidal macrocyclic thiopeptide antibiotic that is produced by Streptomyces azureus and was originally detailed by Donovick et al. in 1955. Thiostrepton shows broad activity against both gram-positive and gram-negative...
LL Z1640-4 is a cis-enol resorcylic acid lactone first reported in 1978 exhibiting both antiviral and antiprotozoan activity. More recently, LL Z1640-2, containing the essential cis-enone system that selectively inhibits TAK 1, has gained literature...
