Our products for cancer research include natural products, antibiotics, chemotherapeutic agents, anti-tumor agents, drug precursors, and immunosuppressants. There are hundreds of high quality compounds to choose from to further your discoveries.
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Sulfasalazine is a synthetic salicylic acid derivative and sulfonamide which can act as an antirhematic and gastrointestinal agent. It is formulated as a prodrug, and is metabolized into active metabolites sulfapyridine and mesalazine (5-aminosalicylic...
Pitavastatin Calcium is the calcium salt formulation of Pitavastatin, a lipophilic statin that inhibits cholesterol synthesis and displays cardioprotective properties. Pitavastatin is often combined with zoledronic acid for oncology applications...
Podophyllotoxin, a natural, non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum species, was first isolated in 1880. Serving as a model for antii-tumor properties, Podophyllotoxin has been used to inhibit the growth of various...
4’-Acetylchrysomycin A and its co-metabolite, 4’-acetylchrysomycin B, were isolated during a screen for antitumor agents. Acetylation of chyrsomycin A reduces cytotoxicity, although both are highly potent (IC50s 64 μg ml-1 for...
Aspulvinone O is a biprenylated butyrolactone isolated from a strain of Paecilomyces by Chinese researchers in 2015.Aspulvinone O is a member of the larger aspulvinone family of secondary metabolites originally isolated from Aspergillusterreus by Seto...
Asperfuran is a dihydrobenzofuran produced by Aspergillus and cold tolerant Penicillium species. Asperfuran has antifungal, cytotoxic and weak chitin synthase activity. Molecular Formula C13H14O3 References Frisvad J.C. et al...
Byssochlamic Acid is a nonadride mycotoxin first isolated from Byssochlamiys fulva by Raistrick and Smith at the Univeristy of London, UK in 1933. Byssochlamic Acid is closely related to the mycotoxins rubratoxin B, produced by Penicillium rubrum, and...
Banksialactone A is the simplest and major analogue of a family of isochromanones isolated from an Australian fungus,Aspergillus banksianus, by researchers at Macquarie University, Australia and Microbial Screening Technologies in 2018. While...
Butyrolactone V is a saturated dibenzylbutyrolactone lignan isolated from a strain of Aspergillus by Lin and collaborators,Xiamen University, China in 2009. Butyrolactone V is moderately active against the parasites, Plasmodium falciparum,Leishmania...
Hecogenin Acetate is a steroidal saponin first published in 1943 by Marker and colleagues at Penn State University and isolated from Agave. Hecogenin Acetate induces cell cycle arrest and senescence, and modulates ERK1/2 phosphorylation and MMP-2...
Hesperidin is a flavonoid produced by citrus species, first published in 1943. Hesperidin has a broad pharmacological profile, including antihyperlipidemic, cardioprotective, antihypertensive and antidiabetic activities, mainly attributed to antioxidant...
IT-143-A is a rare, higher homolog of the piericidin class isolated from a Streptomyces sp. by Taiho Pharmaceuticals incollaboration with Chinese researchers in 1996. IT-143-A is active against the fungus, Aspergillus fumigatus, and the Gram-positive...
