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3-Hydroxy-L-tyrosine methyl ester (melevodopa, L-dopa methyl ester) is a prodrug of levodopa used for the treatment of Parkinson’s disease. L-DOPA methyl ester is a potent competitive antagonist for...
2-Benzoxazolinone is a metabolite produced by rye (Secale cereale) that inhibits germination and growth and causing oxidative damage. 2-Benzoxazolinone has diverse pharmacological activities...
17-Dimethylaminoethylamino-17-demethoxygeldanamycin (DMAG, alvespimycin) is a semi-synthetic derivative of the benzoquinone ansamycin antibiotic isolated from Streptomyces hygroscopicus in which the...
17-allylamino-17-demethoxygeldanamycin (17-AAG), a semi-synthetic derivative of geldanamycin, is a potent antitumor agent that acts by binding to the 90-kDa heat-shock protein (Hsp90) essential to...
Sulfasalazine is a synthetic salicylic acid derivative and sulfonamide which can act as an antirhematic and gastrointestinal agent. It is formulated as a prodrug, and is metabolized into active...
Pitavastatin Calcium is the calcium salt formulation of Pitavastatin, a lipophilic statin that inhibits cholesterol synthesis and displays cardioprotective properties. Pitavastatin is often combined...
Podophyllotoxin, a natural, non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum species, was first isolated in 1880. Serving as a model for antii-tumor properties,...
4’-Acetylchrysomycin A and its co-metabolite, 4’-acetylchrysomycin B, were isolated during a screen for antitumor agents. Acetylation of chyrsomycin A reduces cytotoxicity, although both are highly...
Aspulvinone O is a biprenylated butyrolactone isolated from a strain of Paecilomyces by Chinese researchers in 2015.Aspulvinone O is a member of the larger aspulvinone family of secondary metabolites...
Asperfuran is a dihydrobenzofuran produced by Aspergillus and cold tolerant Penicillium species. Asperfuran has antifungal, cytotoxic and weak chitin synthase activity. Molecular Formula C13 View Details
Byssochlamic Acid is a nonadride mycotoxin first isolated from Byssochlamiys fulva by Raistrick and Smith at the Univeristy of London, UK in 1933. Byssochlamic Acid is closely related to the...
Banksialactone A is the simplest and major analogue of a family of isochromanones isolated from an Australian fungus,Aspergillus banksianus, by researchers at Macquarie University, Australia and...
