Cancer Research

Pentostatin

Pentostatin is a potent antitumor antibiotic isolated from a Streptomyces species. Pentostatin is a potent inhibitor of adenine deaminase and has been used therapeutically as an antitumor agent.Pentostatin is soluble in ethanol, methanol, DMF or DMSO...

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LL-37 (human) Trifluoroacetate Salt

LL-37 (human) Trifluoroacetate Salt (LL-37) is a naturally-occuring antimicrobial peptide that is part of the innate host immune system. It is associated with the epidermis and protects the host from bacterial infection. LL-37 has also demonstrated a...

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Lasalocid Sodium

Lasalocid Sodium is the salt form of Lasalocid, a carboxylic polyether ionophore. The compound has anticancer properties and antibacterial activity. Lasalocid is isolated from Streptomyces lasaliensis, first reported in 1951. It is also known as a...

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Asukamycin

Asukamycin is an unusual trienoic acid amide metabolite produced by Streptomyces nodosus, reported by Omura and colleagues at the Kitasato Institute, Japan, in 1976. Asukamycin belongs to the manumycin class that comprises two trienoic acid amides...

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Melittin

Melittin is the principal toxic component of honey bee venom from Apis mellifera, making up 50% of its dry weight. It is a 26 residue long antimicrobial peptide has an α-helical conformation, and associates strongly with membranes. It has demonstrated...

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Cecropin B

Cecropin B is an antimicrobial peptide originally isolated from insects, but now believed to be naturally produced and found in a large variety of organisms including mammals. It has garnered a lot of interest for its broad-spectrum antiparasitic and...

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Cecropin A

Cecropin A is an antimicrobial peptide originally isolated from insects, but now believed to be naturally produced and found in a large variety of organisms including mammals. It has garnered a lot of interest for its broad-spectrum antiparasitic and...

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Roquefortine C

Roquefortine C is a potent tremorgenic mycotoxin originally isolated from Penicillium roqueforti in 1975 in Japan. Parallel research by Scott and colleagues lead to the structure elucidation of roquefortine C as an unusual diketopiperazine formed by...

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Ochratoxin C

Ochratoxin C is a minor component of the ochratoxin complex produced by several Aspergillus and Penicillium sp. associated with food spoilage. Ochratoxin C is the ethyl ester of ochratoxin A and, despite its relatively low abundance, it is the most...

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Actinopyrone A

Actinopyrone A is a gamma-pyrone compound isolated from a Streptomyces sp.. It shows selective (>10E6 fold) and potent (MIC 0.0001 µg/ml) activity against Helicobacter pylori, the principal cause of peptic ulcer disease. Actinopyrone A was originally...

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Cecropin P1, porcine

Cecropin P1, porcine is the first of the cecropin family to be isolated from a mammal rather than an insect. It has garnered a lot of interest for its antiviral and broad-spectrum antibacterial activities. It is also active against fungi, and has...

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Ochratoxin B

Ochratoxin B is the non-chlorinated analogue of the much more extensively studied ochratoxin A. It is co-produced by the same species of Aspergillus and Penicillium that are associated with food spoilage. Ochratoxin B has received little focused...

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