17-allylamino-17-demethoxygeldanamycin (17-AAG), a semi-synthetic derivative of geldanamycin, is a potent antitumor agent that acts by binding to the 90-kDa heat-shock protein (Hsp90) essential to...
Sulfasalazine is a synthetic salicylic acid derivative and sulfonamide which can act as an antirhematic and gastrointestinal agent. It is formulated as a prodrug, and is metabolized into active...
Pitavastatin Calcium is the calcium salt formulation of Pitavastatin, a lipophilic statin that inhibits cholesterol synthesis and displays cardioprotective properties. Pitavastatin is often combined...
Podophyllotoxin, a natural, non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum species, was first isolated in 1880. Serving as a model for antii-tumor properties,...
Aspulvinone O is a biprenylated butyrolactone isolated from a strain of Paecilomyces by Chinese researchers in 2015.Aspulvinone O is a member of the larger aspulvinone family of secondary metabolites...
Asperfuran is a dihydrobenzofuran produced by Aspergillus and cold tolerant Penicillium species. Asperfuran has antifungal, cytotoxic and weak chitin synthase activity. Molecular Formula C13
Byssochlamic Acid is a nonadride mycotoxin first isolated from Byssochlamiys fulva by Raistrick and Smith at the Univeristy of London, UK in 1933. Byssochlamic Acid is closely related to the...
Butyrolactone V is a saturated dibenzylbutyrolactone lignan isolated from a strain of Aspergillus by Lin and collaborators,Xiamen University, China in 2009. Butyrolactone V is moderately active...
IT-143-A is a rare, higher homolog of the piericidin class isolated from a Streptomyces sp. by Taiho Pharmaceuticals incollaboration with Chinese researchers in 1996. IT-143-A is active against the...
IT-143B is a rare, higher homolog of the piericidin class isolated from a Streptomyces sp. by Taiho Pharmaceuticals incollaboration with Chinese researchers in 1996. IT-143B is active against the...
Limonin is a highly oxygenated terpenoid which forms the core structure of the citrus limonoid metabolites found mostly in the seeds, fruits and peel tissues of citrus. Limonin was first isolated...
Lupeol is a pentacyclic lupane triterpene produced by various fruits, vegetables and other plants, first isolated in 1898 and published in 1907. Lupeol is reported to have very diverse biological...