Chemotherapeutics

Icotinib hydrochloride

Icotinib is an anticancer agent. Icotinib acts as an inhibitor of mutated, overactive or overexpresssed epidermal growth factor receptor (EGFR). Because epidermal growth factors are responsible for controlling cell growth and proliferation, a mutated...

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Imatinib Mesylate

Imatinib mesylate is a tyrosine kinase inhibitor used primarily in the treatment of leukemia. Chronic Myeloid Leukemia (CML) cells contain a hybrid tyrosine kinase BCR/ABL that works to provide the cancer cell with ATP at an uncontrolled rate. Imatinib...

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Ingenol-3-mebutate

Ingenol-3-mebutate is an anticancer agent isolated from Euphorbia peplus used in the treatment of Actinic keratosis. Researchers have shown interest in expanding its anticancer activity, finding promise in its ability to promote proapoptotic effects in...

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Lenalidomide

Lenalidomide is an analogue of the immunomodulatory drug thalidomide with increased potency and fewer adverse effects. It is used in the treatment of hematologic and solid cancers due to its antitumor and anti-angiogenic activities.Mechanism of...

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Mebendazole

Mebendazole is a broad-spectrum anthelmintic used as a treatment for roundworms. More recently it has been investigated as an anti-cancer agent, showing promise in vitro and in mouse models.Mebendazole is soluble in formic acid and practically...

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Metformin hydrochloride

Metformin is a common first line antidiabetic drug, and the only FDA approved member of the biguanide drug class. More recently it has drawn attention from the cancer research sector. Several clinical trials for the use of metformin in the treatment of...

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Methotrexate

Methotrexate is a selective agent for dihydrofolate reductase (DHFR)- transfected cells, and a nucleic acid synthesis inhibitor in protein expression systems, thus can be used as an ancillary material in upstream biomanufacturing applications.  It...

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Methotrexate Sodium

Methotrexate Sodium is a selective agent for dihydrofolate reductase (DHFR)- transfected cells and a nucleic acid synthesis inhibitor in protein expression systems. It is commonly used as an ancillary material in upstream biomanufacturing applications...

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Miconazole

Miconazole is an imidazole antimycotic compound patented in 1968 by Janssen Pharmaceutica.  It inhibits ergosterol synthesis, and a variety of cytochrome P450 enzymes.   It can act as a chemopreventive agent in a mammary cancer cell model...

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Miconazole Nitrate

Miconazole Nitrate is the nitrate salt of Miconazole, an imidazole antimycotic compound patented in 1968 (Janssen Pharmaceutica).  It targets the fungi that cause tinea (ringworm) and athlete’s foot.  It inhibits ergosterol synthesis, and...

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Mitomycin C

Mitomycin C is a bacteriocidal methylazirinopyrroloindoledione antineoplastic antibiotic isolated Streptomyces spp.ApplicationMitomycin C can be used as an inhibitor for cell-free protein biosynthesis research. In addition, Mitomycin C is an efficient...

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Mitoxantrone hydrochloride

Mitoxantrone is a sparingly soluble (0.734 mg/mL) anti-cancer agent.Mechanism of ActionMitoxantrone inhibits division of T-cells, B-cells, and macrophages by preventing DNA repair and synthesis, however, this also occurs in healthy cells.Cancer...

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