Chemotherapeutics

Embelin

Embelin is a benzoquinone derivative from the Japanese Ardisia herb. It is a cell-permeable, small-molecule inhibitor of apoptosis regulator proteins. It is a promising start to a new class of anticancer drugs that target apoptosis regulator proteins. It...

View Details

Emodin

Emodin is a tyrosine kinase inhibitor found in multiple plants with a variety of bioactivity including anti-inflammatory, antiviral, antibacterial and anticancer activity. As an anticancer agent it has drawn attention by showing promising therapeutic...

View Details

Epigallocatechin gallate

Epigallocatechin gallate, the catechin found in green tea (Camellia sinensis), has been reported to have an exhaustive list of promising bioactivity. Researchers have found it to have antiparasitic activity against Leishmania, antiviral activity against...

View Details

Etoposide

Etoposide is an anticancer topoisomerase inhibitor that was derived from the natural product podophyllotoxin extracted from Podophyllum peltatum. It is effective against a variety of cancers, causing DNA damage which leads to apoptosis.Etoposide is very...

View Details

Formonentin

Formononetin is an isoflavonoid isolated from a variety of plants including Astragalus membranaceus, a traditional Chinese medicinal herb. It demonstrates many antimicrobial benefits including anti-inflammatory  and antiviral activity, and...

View Details

Fusarisetin A

Fusarisetin is an unusual pentacyclic metabolite related to equisetin and isolated from a Fusarium. Fusarisetin was identified from a natural product screen using a three-dimensional matrigel-induced bioassay to study acinar morphogenesis. Fusarisetin is...

View Details

Gageostatin A

Gageostatin A is an antimicrobial peptide (AMP) isolated from a marine strain of Bacillus subtilis. Gageostatin A is a linear lipopeptide composed of 7 peptides, and has shown initial bioactivity against pathogenic fungi, gram-positive and gram-negative...

View Details

Germacrone

Germacrone is extracted from the essential oil of Rhizoma Curcuma, and is known for its anticancer and antiviral activity. The activity of germacrone against cancer has been found by different researchers to inhibit angiogenesis, metastasis, cell...

View Details

Herbimycin A

Herbimcyin is a sparingly soluble benzoquinone anti-tumor agent which interacts with the stress-induced chaperone protein Hsp90 (heat shock protein 90).Mechanism of ActionHerbimycin A binds specifically to the heat shock protein Hsp90 and to its...

View Details

Honokiol

Honokiol is a bioactive component of Magnolia obovata, known for its medicinal properties in traditional Asian medicine. Researchers have been interested in its promising antitumor activity, and have reported honokiol inducing apoptosis and inhibiting...

View Details

Hydroxyurea

Hydroxyurea is an antineoplastic chemotherapy drug. It is primarily known for its use in the treatment of the genetic blood disorder, sickle cell anemia, but it is also approved for the treatment of leukemia, skin cancer, and ovarian cancer.Hydroxyurea...

View Details

Icaritin

Icaritin is a hydrolytic product of icariin, and one of the bioactive components of the epimedium genus. It has gained interest mainly from its anticancer activity, including its ability to slow the growth of cancer cells and induce apoptosis. Icaritin...

View Details