Antimicrobials

Verrucofortine

Verrucofortine is a diketopiperazine alkaloid derived from tryptophan and leucine, isolated from Penicillium species. In vivo, verrucofortine exhibits no apparent toxicity in mice even at high doses. Verrucofortine has not been intensively investigated...

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Hydroxypestalotin, 7-

Hydroxypestalotin, a minor analogue of pestalotin, was isolated from Penicillium decumbens. Only the initial report of the metabolite's isolation is available. It is presumed to share a common activity profile with pestalotin.Hydroxypestalotin is soluble...

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Nisin Z

Nisin Z is a natural bacteriocin polypeptide antibiotic known as a lantibiotic. It is a 34-amino acid polycyclic antibacterial peptide.  Nisin Z and Nisin A (Nisin) are two naturally occurring variants of Nisin that are produced by fermentation of...

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Oritavancin Diphosphate

Oritavancin is a semi-synthetic vancomycin analogue active against Gram-positive bacteria. It has a secondary mode of action that allows it to remain active against vancomycin-resistant organisms. It is rapidly bactericidal and effective at killing...

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N-Methylhydroxylamine hydrochloride

N-Methylhydroxylamine hydrochloride is a catalyst commonly used in transamidation, and has been investigated for its radical scavenger abilities as a bacterial growth inhibitor.N-Methylhydroxylamine hydrochloride is soluble in water.Mechanism of...

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Nafcillin sodium salt monohydrate

Nafcillin is a beta-lactamase-resistant drug of the penicillin class.Mechanism of Actionβ-lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a...

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Toltrazuril

Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites in animals, fish, and man.  Its primary metabolites include toltrazuril sulfoxide and toltrazuril sulfone.  Toltrazuril can also be used as an analytical standard in food...

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Ponazuril

Ponazuril is an antiprotozoal agent, specifically a triazine anticoccidial used in veterinary pharmacological research.  It is effective against the apicomplexan group of organisms.  It was originally developed to treat Sarcocystis neurona...

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Florfenicol Amine

Florfenicol Amine is a polar metabolite and degradation product of Florfenicol, specifically formed via hydrolysis of the dichloroacetamide of Florfenicol.  Florfenicol Amine has no antibiotic activity but is an important standard for monitoring...

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Monoacetylphloroglucinol

Monoacetylphloroglucinol (MAPG) is small molecular weight phenolic metabolite belonging to the phloroglucinol (1,3,5-trihydroxybenzene) family, produced by bacteria including Pseudomonas strains. MAPG exhibits a broad range of biological activity albeit...

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Fenbendazole

Fenbendazole is a broad-spectrum antiparasitic used to treat gastrointestinal and respiratory roundworms and tapeworms in livestock and other animals. Fenbendazole is a benzimidazole that acts by binding to tubulin. This blocks microtubules in worms...

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Isepamicin Sulfate

Isepamicin sulfate is an aminoglycoside antibiotic derived from gentamicin B.Mechanism of ActionSimilar to other aminoglycosides, isepamicin sulfate binds to the 30S ribosomal subunit resulting in an inability to read mRNA ultimately producing a faulty...

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