Melittin is the principal toxic component of honey bee venom from Apis mellifera, making up 50% of its dry weight. It is a 26 residue long antimicrobial peptide has an α-helical conformation, and...
Cecropin B is an antimicrobial peptide originally isolated from insects, but now believed to be naturally produced and found in a large variety of organisms including mammals. It has garnered a lot...
Pyridomycin is a potent antibiotic active against mycobacteria and some Gram negative bacteria, originally isolated from Streptomyces abidoflavus by Umezawa group at the NIH Japan in 1953, and since...
Cecropin A is an antimicrobial peptide originally isolated from insects, but now believed to be naturally produced and found in a large variety of organisms including mammals. It has garnered a lot...
Actinopyrone A is a gamma-pyrone compound isolated from a Streptomyces sp. It shows selective (>106 fold) and potent (MIC=0.0001 µg/ml) activity against Helicobacter pylori, the principal cause of...
Calcimycin (syn. A23187) is a potent Ca2+ ionophore and carboxylic acid antibiotic isolated from the soil bacterium Streptomyces chartreusis (NRRL 3882) in 1974. It was isolated from the bacterial...
Cecropin P1, porcine is the first of the cecropin family to be isolated from a mammal rather than an insect. It has garnered a lot of interest for its antiviral and broad-spectrum antibacterial...
Doramectin is a biosynthetic avermectin derived from a mutant strain of Streptomyces avermitilis, supplemented with a cyclohexylcaboxylic acid starting unit. Doramectin was developed as an...
Ansatrienin A, isolated from a Streptomyces sp., is closely related to the cytotrienins and trienomycins. It displays potent activity against tumor cell lines and inhibits osteoclastic bone...
Ansatrienin B, also known as Mycotrienin II and Antibiotic T 23II, was isolated from a Streptomyces sp.. Closely related to the cytotrienins and trienomycins, it displays potent activity against...
Acriflavine Hydrochloride (syn: Acriflavine HCl) is the hydrochloride salt of Acriflavine, a mixture of 3,6-diamino-10-methylacridium (acriflavin) and 3,6-diaminoacridine (proflavin). It was...
Methacycline is a semi-synthetic tetracycline prepared by dehydration of the 6-hydroxy group of oxytetracycline to yield an exocyclic 6-methylene. Like all tetracyclines, methacycline shows broad...