Antimicrobials

Sulbactam

Sulbactam is an irreversible inhibitor of several bacterial penicillinases and cephalosporinases. In the presence of low concentrations of sulbactam, ampicillin and other β-lactams readily inhibit the growth of a variety of resistant bacteria that...

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Chlorhexidine diacetate salt

Chlorhexidine diacetate salt is an antiseptic antibacterial agent commonly used as a disinfectant in eye drops, deodorants, creams, and others. Chlorhexidine is also used as an active ingredient in mouthwash to prevent and control dental plaque.This...

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Nigericin Sodium

Nigericin Sodium is an antibiotic and potassium ionophore derived from Streptomyces hygroscopicus. It exchanges potassium for hydrogen ions across biological membranes in a similar manner to Valinomycin.  Nigericin Sodium also acts as an ionophore...

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Pyrocoll

Pyrocoll is a small secondary metabolite formed by the dimerisation of pyrrole-2-carboxylic acid and produced by many Streptomyces species. Pyrocoll is an important dereplication standard in discovery, displaying a highly distinctive UV spectrum. The...

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Gilvocarcin M

Gilvocarcin M is the minor analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces sp.. Gilvocarcin M contains a methyl group in the 8-position, and is less active than the vinyl analogue (gilvocarcin V), which is thought to...

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Gilvocarcin V

Gilvocarcin V is the major analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces sp.. Gilvocarcin V contains a vinyl group in the 8-position, and is the most potent analogue of the complex. It is thought to act as an...

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Quinomycin A

Quinomycin A is a cyclic depsipeptide metabolite. Quinomycin A has broad activity against bacteria, fungi and viruses, and has found application as an antitumor agent. Quinomycin A acts by bifunctional intercalation of nucleic acids. Quinomycin A is an...

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Quinaldopeptin

Quinaldopeptin is a symmetrical, cyclic decapeptide from an Amycolatopsis sp. that is a bis-intercalator of DNA, exhibiting strong in vitro antimicrobial and cytotoxic activity. Quinaldopeptin significantly prolongs the survival time of mice inoculated...

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Cytochalasin A

Cytochalasin A is one of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, giving rise to pronounced morphogenic activity in animals and plants. Despite the...

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Methacycline hydrochloride

Methacycline HCl is a member of the tetracycline antibiotics and is more active against Gram-negative and Gram-positive bacteria than tetracycline and demethylchlortetracycline.ApplicationMethacycline HCl can be used as a synthetic precursor of...

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Terrecyclic Acid

Terrecyclic acid is a tricyclic sesquiterpene antibiotic produced by Aspergillus terreus, first reported by researchers at the Universities of Osaka and Tokyo in 1982. Terrecyclic acid A had a wide antimicrobial spectrum of rather weak activities...

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Leucinostatin A

Leucinostatin A is the major component of an atypical nonapeptide complex produced by Paecilomyces lilacinus, first reported in 1973. Leucinostatins display broad bioactivity against Gram-positive bacteria, fungi, plants and tumor cell lines...

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