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Antibacterials

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  • Anacardic Acid

    Anacardic Acid

    Anacardic acid is a histone acetyltransferase (HAT) inhibitor that is derived from cashew shells. Anacardic acid is associated with anti-inflammatory, anti-tumor, molluscicidal, and anti-microbial activity. Anacardic acid is a common inhibitor of several...

  • Ceftaroline Fosamil

    Ceftaroline Fosamil

    Ceftaroline Fosamil is a fifth-generation cephalosporin, a broad-spectrum β-lactam active against MRSA and respiratory pathogens.  It carries the trade name Teflaro (US) or Zinforo i(Europe).  It can be used against the bacteria causing...

  • Nitrofurantoin Sodium

    Nitrofurantoin Sodium

    Nitrofurantoin Sodium is the sodium salt of Nitrofurantoin, a broad-spectrum nitrofuran antibiotic that is used as a substrate for bacterial glycoprotein nitrofuran reductase. It is bacteriostatic against Gram-positive and Gram-negative bacteria. The...

  • Framycetin Sulfate

    Framycetin Sulfate

    Framycetin Sulfate (syn: Neomycin B Sulfate) is the sulfate salt form of Neomycin, a broad-spectrum aminoglycoside antibiotic derived from Streptomyces fradiae.  Neomycin B is ~ 65% more active than its stereoisomer, Neomycin C, and ~ 90% more...

  • Flomoxef Sodium

    Flomoxef Sodium

    Flomoxef Sodium is a β-lactam inhibitor and member of the oxacephem family and exhibits antibiotic properties.  It has been used for respiratory infections and bone diseases (ie osteoporosis).  It was synthesized in 1982 by Shionogi &...

  • Temocillin Disodium

    Temocillin Disodium

    Temocillin Disodium is the disodium salt of Temocillin, a semisynthetic, β-­lactamase-resistant carboxypenicillin antimicrobial. Temocillin is the 6-alpha-methoxy derivative of ticarcillin.  Temocillin is is used as an alternative to...

  • Pexiganan acetate

    Pexiganan acetate

    Pexiganan is an antimicrobial peptide (AMP) that is effective against a broad spectrum of bacteria including aerobic and anaerobic, gram-positive and gram-negative. Bacterial resistance to pexiganan is very unlikely to develop.Mechanism of...

  • Ceftazidime Solubilized

    Ceftazidime Solubilized

    Ceftazidime Solubilized is a semi-synthetic, broad-spectrum, third-generation, β-lactam cephalosporin.   Patented in 1978, it came into commercial use in 1984.   Ceftazidime is bactericidal in action, inhibiting enzymes...

  • Ceftiofur Hydrochloride

    Ceftiofur Hydrochloride

    Ceftiofur Hydrochloride is the hydrochloride salt of Ceftiofur, a broad-spectrum, third-generation β-lactamase resistant cephalosporin commonly used in veterinary research applications that was first described in 1987.  Its metabolite...

  • Pristinamycin

    Pristinamycin

    Pristinamycin is a streptogramin antibiotic. It is a mixture of Pristinamycin IA (a macrolide) and Pristinamycin IIA (streptogramin A), a depsipeptide). PI and PII are structurally unrelated but synergistic components. They are co-produced naturally in a...

  • Doripenem Hydrate

    Doripenem Hydrate

    Doripenem Hydrate is a β-lactam antibiotic of the carbapenem class, specifically a 1-β-methyl carbapenem.  It is effective against extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae, a microbe resistant to many first...

  • Nalidixic Acid Sodium, CulturePure

    Nalidixic Acid Sodium, CulturePure

    Nalidixic Acid Sodium, CulturePure is a synthetic 1,8-naphthyridone antibiotic similar in structure and mechanism to quinolones, the commercial preparation of which was developed by Sanofi Aventis.  The product is commonly used as a selective agent...

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