Antibacterials

Oxolinic Acid

Oxolinic acid is a synthetic quinolone antibiotic. It is insoluble in water and soluble in dilute alkali solutions. Mechanism of Action Fluoroquinolone antibiotics target bacterial DNA gyrase, an enzyme which reduces DNA strain during replication...

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Tobramycin Sulfate, USP

Tobramycin Sulfate, USP is an aminoglycoside antibiotic derived from Streptomyces tenebrarius. Tobramycin is a member of a broad-spectrum antibiotic complex, nebramycin, that was originally isolated in 1967 by Eli Lilly and Company.  The nebramycin...

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Trimethoprim Lactate

Trimethoprim Lactate is a synthetic derivative of trimethoxybenzyl-pyrimidine with bacteriostatic and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, Trimethoprim binds tightly to the bacterial enzyme, blocking...

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Trimethoprim

Trimethoprim is a synthetic derivative of trimethoxybenzyl-pyrimidine with bacteriostatic and antiprotozoal properties. As a dihydrofolate reductase inhibitor, trimethoprim binds tightly to the bacterial enzyme, blocking the production...

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Fusidic Acid Sodium

Fusidic Acid Sodium is a bacteriostatic steroid triterpenoid antibiotic of the fusidane class which inhibits protein synthesis in Gram-positive bacteria.  It can be used to study the effects of compound combinations on bacterial growth, and gene...

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Methicillin Sodium

Methicillin Sodium is a narrow-spectrum β-lactam antibiotic belonging to the penicillin family and is a semi-synthetic derivative of penicillin.  It was manufactured in the late 1950s.  It is commonly used as a selective agent in pathogen...

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Vancomycin

Vancomycin is a glycopeptide antibiotic derived from Streptomyces orientalis that was discovered in 1953 from a soil sample found in Borneo. It is effective against gram-positive bacteria such as Staphylococcus aureus and is used in studies of...

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Norfloxacin

Norfloxacin is a first-generation synthetic fluoroquinolone antibiotic. Mechanism of Action Norfloxacin indirectly inhibits DNA gyrase by binding to nearby DNA substrate. DNA gyrase is an essential DNA replication enzyme which reduces DNA strain...

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Polymyxin B Sulfate, USP

Polymyxin B Sulfate, USP is a polypeptide antibiotic mixture composed of Polymyxins B1, B2, and B3 fractions, with B1 and B2 fractions comprising the majority of the mixture. Polymyxin B components are structurally identical with the exception of a...

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Nalidixic Acid

Nalidixic Acid is a synthetic 1,8-naphthyridone antibiotic similar in structure and mechanism to quinolones.  It can be used as a tool to study bacterial division regulation.  The compound can also be used in the RADAR assay, a method for...

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Lincomycin Hydrochloride, USP

Lincomycin Hydrochloride, USP is the hydrochloride salt form of Lincomycin provided as the monohydrate.  Lincomycin is a naturally occurring lincosamide isolated from Streptomyces licolnensis by researchers at Upjohn in 1962. This class of...

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Fosfomycin Sodium

Fosfomycin Sodium is broad-spectrum phosphoenolpyruvate analog antibiotic.  It has a chemically unique structure unlike any other antibacterial agent.  Fosfomycin has been found to have an immunomodulatory effect on human B-cell activation...

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