Antibacterials

Colistin Sulfate, USP

Colistin Sulfate, USP (syn: polymyxin E) is a cationic, cyclic polypeptide antibiotic belonging to the polymyxin family. It is a natural product discovered in 1949 that is nonribosomally synthesized by Bacillus polymyxa subspecies colistinus...

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Colistin Sodium Methanesulfonate

Colistin Sodium Methanesulfonate is considered an inactive prodrug of colistin, which means it is inactive until converted into colistin by cellular enzymes. It is prepared by the reaction of colistin with formaldehyde, followed by sodium bisulfate. It...

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Siomycin A

Siomycin is a macrocyclic thiopeptide antibiotic with potent and selective antibacterial activity first isolated from the fermentation product of Streptomyces sioyaensis by Nishimura in 1959. This member of the thiostrepton family is a potent inhibitor...

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Clindamycin Phosphate

Clindamycin Phosphate (Clindamycin-2-phosphate) is a broad-spectrum antibiotic and antiparasitic agent.  It is a semi-synthetic derivative of Lincomycin, a natural lincosamide from Streptomyces lincolnensis.  Clindamycin Phosphate is freely...

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Cefotetan

Cefotetan is a cephamycin antibiotic grouped with the second-generation cephalosporins. TOKU-E offers two forms of cefotetan: Cefotetan (C012) Cefotetan Disodium (C117) Cefotetan is sparingly soluble in water (0.51 mg/mL) and cefotetan disodium is...

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Clindamycin Hydrochloride

Clindamycin Hydrochloride is a broad-spectrum antibiotic and antiparasitic agent.  It is a semi-synthetic analog of lincomycin, a natural lincosamide isolated from Streptomyces lincolnensis in 1966.  Anhydrous Clindamycin Hydrochloride is...

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D-Cycloserine

D-Cycloserine is an amino acid analog antibiotic. D-Cycloserine acts as a competitive inhibitor of D-alanine, an essential amino acid during peptidoglycan synthesis.  It is a broad-spectrum antibiotic that can be used as a selective agent in several...

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Cephalothin Sodium, USP

Cephalothin Sodium, USP is a semisynthetic, β-lactam, first-generation cephalosporin antibiotic with bactericidal activity. It is effective against Gram-positive and Gram-negative bacteria.  Cephalothin Sodium is inactivated by cephalosporinase...

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Lincomycin Hydrochloride, EP

Lincomycin Hydrochloride, EP is the hydrochloride form of Lincomycin, provided as the monohydrate. Lincomycin is a naturally occurring lincosamide isolated from Streptomyces licolnensis by researchers at Upjohn in 1962. This class of antibacterial...

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Kanamycin Sulfate, USP

Kanamycin Sulfate, USP is a semi-synthetic, broad-spectrum aminoglycoside antibiotic.  Kanamycin was isolated from the soil bacterium Streptomyces kanamyceticus in 1957 by Hamao Umezawa at the institute of Microbial Chemistry (Tokyo) during an...

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Cefsulodin Sodium

Cefsulodin Sodium is a third-generation cephalosporin antibiotic.  The compound has been optimized via industrial HPLC to remove significant quantities of 7-aminocephalosporanic acid (7-ACA), a key impurity in Cefsulodin synthesis that can cause...

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Kanamycin Acid Sulfate, BP

Kanamycin Acid Sulfate, BP is an aminoglycoside antibiotic often used to select for bacteria which have been successfully transformed with a plasmid conferring kanamycin resistance. Kanamycin is very soluble in aqueous solution at 92.3 mg/mL. Standard...

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