SKU: A193  / 
    CAS Number: 23214-93-9

    1-Acetylchloramphenicol

    5,613,273.75₫ - 19,655,782.50₫

    1-Acetylchloramphenicol is an isomer of chloramphenicol acetate, a naturally-occurring co-metabolite of chloramphenicol in Streptomyces venezuelae albeit with significantly lower potency. Chloramphenicol acetate is the major product of chloramphenicol acetyltransferase, the major resistance mechanism to chloramphenicol.

    Molecular Formula  C13H14Cl2N2O6
    References

    Gross F et al (2002)  Isolation of 3′-O-acetylchloramphenicol: A possible intermediate in chloramphenicol biosynthesis.  Bioorg. Med. Chem. Letters 12: 283

    Shaw WV and Leslie AGW (1991)  Chloramphenicol acetyltransferase Ann. Rev. Biophys. Biophys. Chem. 20:363