1-Acetylchloramphenicol is an isomer of chloramphenicol acetate, a naturally-occurring co-metabolite of chloramphenicol in Streptomyces venezuelae albeit with significantly lower potency. Chloramphenicol acetate is the major product of chloramphenicol acetyltransferase, the major resistance mechanism to chloramphenicol.
| Molecular Formula | C13H14Cl2N2O6 |
| References |
Gross F et al (2002) Isolation of 3′-O-acetylchloramphenicol: A possible intermediate in chloramphenicol biosynthesis. Bioorg. Med. Chem. Letters 12: 283 Shaw WV and Leslie AGW (1991) Chloramphenicol acetyltransferase Ann. Rev. Biophys. Biophys. Chem. 20:363 |
