Bioactive small molecules are organic compounds that have a low molecular weight (900 daltons). Most pharmaceutical drugs are small molecules. Larger structures such as nucleic acids, proteins, and many polysaccharides are not small molecules.
Leptomycin B is the dominant member of the Leptomycin class, secondary metabolites isolated from selected Streptomyces strains. It is a bioactive small molecule with antifungal and antibacterial...
Miconazole Nitrate is the nitrate salt of Miconazole, an imidazole antimycotic compound patented in 1968 (Janssen Pharmaceutica). It targets the fungi that cause tinea (ringworm) and athlete’s foot...
Tilmicosin is a macrolide semisynthetic macrolide antibiotic and small molecule synthesized from Tylosin. It is used in veterinary research studies against the bovine and ovine pathogen Mannheimia...
Anidulafungin is a semi-synthetic echinocandin derivative and antifungal effective against Candida spp. Anidulafungin inhibits fungal cell wall synthesis. It is useful in pharmacotherapy and cell...
Amphotericin B, USP (syn: Fungizone) is a polyene macrolide aminoglycoside broad-spectrum antimycotic. This bioactive natural product was isolated from soil collected from Orinoco River (Venezuela)...
Mupirocin, USP is a carboxylic acid with bacteriostatic/bactericidal properties. This compound formerly known as pseudomonic acid A is produced by Pseudomonas fluorescens and is a...
Midecamycin is an naturally occurring, broad-spectrum acetoxy-substituted macrolide antibiotic similar in structure to erythromycin. An acetoxy group is substituted on position 9 of the 16-membered...
Clotrimazole is a broad-spectrum antifungal belonging to the imidazole subclass of azole compounds. These compounds interfere with the biosynthesis of ergosterol, a major membrane component of the...
4-CPPU (CPPU) is a highly active plant growth regulator of the cytokine class that increases chlorophyll biosynthesis, cell division and cell expansion. It can increase fruit set and fruit...
Florfenicol is a fluorinated synthetic analog of Thiamphenicol, belonging to the amphenicol class which also contains Choramphenicol. It is metabolized to Florfenicol Amine. The compound is a...
Metronidazole is a bioactive small molecule and broad-spectrum nitromidazole antibiotic used against anaerobic bacteria and parasites. The hydroxy metabolite, 1-(2-hydroxy-ethyl)-2-hydroxy...
Flumequine is a broad-spectrum, first-generation fluoroquinolone commonly used in veterinary research. It was patented in 1973 by Riker Labs. Flumequine is freely soluble in alkaline solutions and...
